Swaisland HC - Search Results

1

Metabolic disposition of AZD8931, an oral equipotent inhibitor of EGFR, HER2 and HER3 signalling, in rat, dog and man.

Ballard P, Swaisland HC, Malone MD, Sarda S, Ghiorghiu S, Wilbraham D. Ballard P, et al. Among authors: swaisland hc. Xenobiotica. 2014 Dec;44(12):1083-98. doi: 10.3109/00498254.2014.938257. Epub 2014 Jul 9. Xenobiotica. 2014. PMID: 25007130

2

Metabolic disposition of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, in rat, dog and man.

McKillop D, Hutchison M, Partridge EA, Bushby N, Cooper CM, Clarkson-Jones JA, Herron W, Swaisland HC. McKillop D, et al. Among authors: swaisland hc. Xenobiotica. 2004 Oct;34(10):917-34. doi: 10.1080/00498250400009171. Xenobiotica. 2004. PMID: 15764411 Clinical Trial.

3

Pharmacokinetics of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, in rat and dog.

McKillop D, Partridge EA, Hutchison M, Rhead SA, Parry AC, Bardsley J, Woodman HM, Swaisland HC. McKillop D, et al. Among authors: swaisland hc. Xenobiotica. 2004 Oct;34(10):901-15. doi: 10.1080/00498250400009189. Xenobiotica. 2004. PMID: 15764410

4

Disposition and metabolism of the specific endothelin A receptor antagonist zibotentan (ZD4054) in healthy volunteers.

Clarkson-Jones JA, Kenyon AS, Kemp J, Lenz EM, Oliver SD, Swaisland H. Clarkson-Jones JA, et al. Xenobiotica. 2012 Apr;42(4):363-71. doi: 10.3109/00498254.2011.624204. Epub 2011 Oct 20. Xenobiotica. 2012. PMID: 22014279

5

In vitro metabolism of the specific endothelin-A receptor antagonist ZD4054 and clinical drug interactions between ZD4054 and rifampicin or itraconazole in healthy male volunteers.

Swaisland HC, Oliver SD, Morris T, Jones HK, Bakhtyari A, Mackey A, McCormick AD, Slamon D, Hargreaves JA, Millar A, Taboada MT. Swaisland HC, et al. Xenobiotica. 2009 Jun;39(6):444-56. doi: 10.1080/00498250902810944. Xenobiotica. 2009. PMID: 19480550 Clinical Trial.

6

In vitro evaluation of the inhibition and induction potential of olaparib, a potent poly(ADP-ribose) polymerase inhibitor, on cytochrome P450.

McCormick A, Swaisland H, Reddy VP, Learoyd M, Scarfe G. McCormick A, et al. Xenobiotica. 2018 Jun;48(6):555-564. doi: 10.1080/00498254.2017.1346332. Epub 2017 Jul 25. Xenobiotica. 2018. PMID: 28657402

7

Pharmacokinetics and tolerability of the orally active selective epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in healthy volunteers.

Swaisland H, Laight A, Stafford L, Jones H, Morris C, Dane A, Yates R. Swaisland H, et al. Clin Pharmacokinet. 2001;40(4):297-306. doi: 10.2165/00003088-200140040-00005. Clin Pharmacokinet. 2001. PMID: 11368294

8

In vitro assessment of the roles of drug transporters in the disposition and drug-drug interaction potential of olaparib.

McCormick A, Swaisland H. McCormick A, et al. Xenobiotica. 2017 Oct;47(10):903-915. doi: 10.1080/00498254.2016.1241449. Epub 2016 Oct 26. Xenobiotica. 2017. PMID: 27684210

9

Single-dose clinical pharmacokinetic studies of gefitinib.

Swaisland HC, Smith RP, Laight A, Kerr DJ, Ranson M, Wilder-Smith CH, Duvauchelle T. Swaisland HC, et al. Clin Pharmacokinet. 2005;44(11):1165-77. doi: 10.2165/00003088-200544110-00004. Clin Pharmacokinet. 2005. PMID: 16231967

10

Olaparib tablet formulation: effect of food on the pharmacokinetics after oral dosing in patients with advanced solid tumours.

Plummer R, Swaisland H, Leunen K, van Herpen CM, Jerusalem G, De Grève J, Lolkema MP, Soetekouw P, Mau-Sørensen M, Nielsen D, Spicer J, Fielding A, So K, Bannister W, Molife LR. Plummer R, et al. Cancer Chemother Pharmacol. 2015 Oct;76(4):723-9. doi: 10.1007/s00280-015-2836-2. Epub 2015 Aug 5. Cancer Chemother Pharmacol. 2015. PMID: 26242220 Clinical Trial.

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