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Molecular pathogenesis of spondylocheirodysplastic Ehlers-Danlos syndrome caused by mutant ZIP13 proteins.
Bin BH, Hojyo S, Hosaka T, Bhin J, Kano H, Miyai T, Ikeda M, Kimura-Someya T, Shirouzu M, Cho EG, Fukue K, Kambe T, Ohashi W, Kim KH, Seo J, Choi DH, Nam YJ, Hwang D, Fukunaka A, Fujitani Y, Yokoyama S, Superti-Furga A, Ikegawa S, Lee TR, Fukada T. Bin BH, et al. Among authors: fukada t. EMBO Mol Med. 2014 Aug;6(8):1028-42. doi: 10.15252/emmm.201303809. EMBO Mol Med. 2014. PMID: 25007800 Free PMC article.
The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways.
Fukada T, Civic N, Furuichi T, Shimoda S, Mishima K, Higashiyama H, Idaira Y, Asada Y, Kitamura H, Yamasaki S, Hojyo S, Nakayama M, Ohara O, Koseki H, Dos Santos HG, Bonafe L, Ha-Vinh R, Zankl A, Unger S, Kraenzlin ME, Beckmann JS, Saito I, Rivolta C, Ikegawa S, Superti-Furga A, Hirano T. Fukada T, et al. PLoS One. 2008;3(11):e3642. doi: 10.1371/journal.pone.0003642. Epub 2008 Nov 5. PLoS One. 2008. PMID: 18985159 Free PMC article.
A Rac GTPase-activating protein, MgcRacGAP, is a nuclear localizing signal-containing nuclear chaperone in the activation of STAT transcription factors.
Kawashima T, Bao YC, Minoshima Y, Nomura Y, Hatori T, Hori T, Fukagawa T, Fukada T, Takahashi N, Nosaka T, Inoue M, Sato T, Kukimoto-Niino M, Shirouzu M, Yokoyama S, Kitamura T. Kawashima T, et al. Among authors: fukada t. Mol Cell Biol. 2009 Apr;29(7):1796-813. doi: 10.1128/MCB.01423-08. Epub 2009 Jan 21. Mol Cell Biol. 2009. PMID: 19158271 Free PMC article.
Zinc suppresses Th17 development via inhibition of STAT3 activation.
Kitabayashi C, Fukada T, Kanamoto M, Ohashi W, Hojyo S, Atsumi T, Ueda N, Azuma I, Hirota H, Murakami M, Hirano T. Kitabayashi C, et al. Among authors: fukada t. Int Immunol. 2010 May;22(5):375-86. doi: 10.1093/intimm/dxq017. Epub 2010 Mar 9. Int Immunol. 2010. PMID: 20215335
212 results