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Page 1
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.
Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stöger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Hoeksema MA, et al. Among authors: levels jh. EMBO Mol Med. 2014 Sep;6(9):1124-32. doi: 10.15252/emmm.201404170. EMBO Mol Med. 2014. PMID: 25007801 Free PMC article.
Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity.
Pols TW, Ottenhoff R, Vos M, Levels JH, Quax PH, Meijers JC, Pannekoek H, Groen AK, de Vries CJ. Pols TW, et al. Among authors: levels jh. Biochem Biophys Res Commun. 2008 Feb 22;366(4):910-6. doi: 10.1016/j.bbrc.2007.12.039. Epub 2007 Dec 18. Biochem Biophys Res Commun. 2008. PMID: 18086558
Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man.
Holleboom AG, Karlsson H, Lin RS, Beres TM, Sierts JA, Herman DS, Stroes ES, Aerts JM, Kastelein JJ, Motazacker MM, Dallinga-Thie GM, Levels JH, Zwinderman AH, Seidman JG, Seidman CE, Ljunggren S, Lefeber DJ, Morava E, Wevers RA, Fritz TA, Tabak LA, Lindahl M, Hovingh GK, Kuivenhoven JA. Holleboom AG, et al. Among authors: levels jh. Cell Metab. 2011 Dec 7;14(6):811-8. doi: 10.1016/j.cmet.2011.11.005. Cell Metab. 2011. PMID: 22152306 Free PMC article.
Pro-atherogenic lipid changes and decreased hepatic LDL receptor expression by tocilizumab in rheumatoid arthritis.
Strang AC, Bisoendial RJ, Kootte RS, Schulte DM, Dallinga-Thie GM, Levels JH, Kok M, Vos K, Tas SW, Tietge UJ, Müller N, Laudes M, Gerlag DM, Stroes ES, Tak PP. Strang AC, et al. Among authors: levels jh. Atherosclerosis. 2013 Jul;229(1):174-81. doi: 10.1016/j.atherosclerosis.2013.04.031. Epub 2013 May 11. Atherosclerosis. 2013. PMID: 23746537 Clinical Trial.
Myeloid Kdm6b deficiency results in advanced atherosclerosis.
Neele AE, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Prange KHM, Chen HJ, Van den Bossche J, van Roomen CPPA, Shami A, Levels JHM, Kroon J, Lucas T, Dimmeler S, Lutgens E, de Winther MPJ. Neele AE, et al. Atherosclerosis. 2018 Aug;275:156-165. doi: 10.1016/j.atherosclerosis.2018.05.052. Epub 2018 Jun 1. Atherosclerosis. 2018. PMID: 29908485 Free article.
N-Glycosylation Defects in Humans Lower Low-Density Lipoprotein Cholesterol Through Increased Low-Density Lipoprotein Receptor Expression.
van den Boogert MAW, Larsen LE, Ali L, Kuil SD, Chong PLW, Loregger A, Kroon J, Schnitzler JG, Schimmel AWM, Peter J, Levels JHM, Steenbergen G, Morava E, Dallinga-Thie GM, Wevers RA, Kuivenhoven JA, Hand NJ, Zelcer N, Rader DJ, Stroes ESG, Lefeber DJ, Holleboom AG. van den Boogert MAW, et al. Circulation. 2019 Jul 23;140(4):280-292. doi: 10.1161/CIRCULATIONAHA.118.036484. Epub 2019 May 23. Circulation. 2019. PMID: 31117816
71 results