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An optimized, synthetic DNA vaccine encoding the toxin A and toxin B receptor binding domains of Clostridium difficile induces protective antibody responses in vivo.
Baliban SM, Michael A, Shammassian B, Mudakha S, Khan AS, Cocklin S, Zentner I, Latimer BP, Bouillaut L, Hunter M, Marx P, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, Kutzler MA. Baliban SM, et al. Among authors: weiner db. Infect Immun. 2014 Oct;82(10):4080-91. doi: 10.1128/IAI.01950-14. Epub 2014 Jul 14. Infect Immun. 2014. PMID: 25024365 Free PMC article.
Genetic infection induces protective in vivo immune responses.
Williams WV, Boyer JD, Merva M, Livolsi V, Wilson D, Wang B, Weiner DB. Williams WV, et al. Among authors: weiner db. DNA Cell Biol. 1993 Oct;12(8):675-83. doi: 10.1089/dna.1993.12.675. DNA Cell Biol. 1993. PMID: 8397826
Developing DNA vaccines that call to dendritic cells.
Kutzler MA, Weiner DB. Kutzler MA, et al. Among authors: weiner db. J Clin Invest. 2004 Nov;114(9):1241-4. doi: 10.1172/JCI23467. J Clin Invest. 2004. PMID: 15520855 Free PMC article. Review.
Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help.
Kutzler MA, Robinson TM, Chattergoon MA, Choo DK, Choo AY, Choe PY, Ramanathan MP, Parkinson R, Kudchodkar S, Tamura Y, Sidhu M, Roopchand V, Kim JJ, Pavlakis GN, Felber BK, Waldmann TA, Boyer JD, Weiner DB. Kutzler MA, et al. Among authors: weiner db. J Immunol. 2005 Jul 1;175(1):112-23. doi: 10.4049/jimmunol.175.1.112. J Immunol. 2005. PMID: 15972637
531 results