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AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.
Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL. Lanner JT, et al. Among authors: monroe to. Nat Med. 2012 Jan 8;18(2):244-51. doi: 10.1038/nm.2598. Nat Med. 2012. PMID: 22231556 Free PMC article.
PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia.
Monroe TO, Garrett ME, Kousi M, Rodriguiz RM, Moon S, Bai Y, Brodar SC, Soldano KL, Savage J, Hansen TF, Muzny DM, Gibbs RA, Barak L, Sullivan PF, Ashley-Koch AE, Sawa A, Wetsel WC, Werge T, Katsanis N. Monroe TO, et al. Nat Commun. 2020 Nov 19;11(1):5903. doi: 10.1038/s41467-020-19637-5. Nat Commun. 2020. PMID: 33214552 Free PMC article.
A steroid receptor coactivator stimulator (MCB-613) attenuates adverse remodeling after myocardial infarction.
Mullany LK, Rohira AD, Leach JP, Kim JH, Monroe TO, Ortiz AR, Stork B, Gaber MW, Sarkar P, Sikora AG, Rosengart TK, York B, Song Y, Dacso CC, Lonard DM, Martin JF, O'Malley BW. Mullany LK, et al. Among authors: monroe to. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31353-31364. doi: 10.1073/pnas.2011614117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229578 Free PMC article.
Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function.
Lee CS, Georgiou DK, Dagnino-Acosta A, Xu J, Ismailov II, Knoblauch M, Monroe TO, Ji R, Hanna AD, Joshi AD, Long C, Oakes J, Tran T, Corona BT, Lorca S, Ingalls CP, Narkar VA, Lanner JT, Bayle JH, Durham WJ, Hamilton SL. Lee CS, et al. Among authors: monroe to. J Biol Chem. 2014 Sep 12;289(37):25556-70. doi: 10.1074/jbc.M114.586289. Epub 2014 Jul 22. J Biol Chem. 2014. PMID: 25053409 Free PMC article.
16 results