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ABCB5 is a limbal stem cell gene required for corneal development and repair.
Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY. Ksander BR, et al. Among authors: guo q. Nature. 2014 Jul 17;511(7509):353-7. doi: 10.1038/nature13426. Epub 2014 Jul 2. Nature. 2014. PMID: 25030174 Free PMC article.
Targeting the ABC transporter ABCB5 sensitizes glioblastoma to temozolomide-induced apoptosis through a cell-cycle checkpoint regulation mechanism.
Lee CAA, Banerjee P, Wilson BJ, Wu S, Guo Q, Berg G, Karpova S, Mishra A, Lian JW, Tran J, Emmerich M, Murphy GF, Frank MH, Frank NY. Lee CAA, et al. Among authors: guo q. J Biol Chem. 2020 May 29;295(22):7774-7788. doi: 10.1074/jbc.RA120.013778. Epub 2020 Apr 20. J Biol Chem. 2020. PMID: 32317280 Free PMC article.
Clinical Manifestations.
Wu J, Li Y, Zhou Z, Xia H, Chen N, Guo Q. Wu J, et al. Among authors: guo q. Alzheimers Dement. 2024 Dec;20 Suppl 3:e089523. doi: 10.1002/alz.089523. Alzheimers Dement. 2024. PMID: 39750447
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