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Large-scale filament formation inhibits the activity of CTP synthetase.
Barry RM, Bitbol AF, Lorestani A, Charles EJ, Habrian CH, Hansen JM, Li HJ, Baldwin EP, Wingreen NS, Kollman JM, Gitai Z. Barry RM, et al. Among authors: hansen jm. Elife. 2014 Jul 16;3:e03638. doi: 10.7554/eLife.03638. Elife. 2014. PMID: 25030911 Free PMC article.
Human CTP synthase filament structure reveals the active enzyme conformation.
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM. Lynch EM, et al. Among authors: hansen jm. Nat Struct Mol Biol. 2017 Jun;24(6):507-514. doi: 10.1038/nsmb.3407. Epub 2017 May 1. Nat Struct Mol Biol. 2017. PMID: 28459447 Free PMC article.
Structural basis for isoform-specific inhibition of human CTPS1.
Lynch EM, DiMattia MA, Albanese S, van Zundert GCP, Hansen JM, Quispe JD, Kennedy MA, Verras A, Borrelli K, Toms AV, Kaila N, Kreutter KD, McElwee JJ, Kollman JM. Lynch EM, et al. Among authors: hansen jm. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2107968118. doi: 10.1073/pnas.2107968118. Proc Natl Acad Sci U S A. 2021. PMID: 34583994 Free PMC article.
Modular repeat protein sculpting using rigid helical junctions.
Brunette TJ, Bick MJ, Hansen JM, Chow CM, Kollman JM, Baker D. Brunette TJ, et al. Among authors: hansen jm. Proc Natl Acad Sci U S A. 2020 Apr 21;117(16):8870-8875. doi: 10.1073/pnas.1908768117. Epub 2020 Apr 3. Proc Natl Acad Sci U S A. 2020. PMID: 32245816 Free PMC article.
BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Witus SR, Burrell AL, Farrell DP, Kang J, Wang M, Hansen JM, Pravat A, Tuttle LM, Stewart MD, Brzovic PS, Chatterjee C, Zhao W, DiMaio F, Kollman JM, Klevit RE. Witus SR, et al. Among authors: hansen jm. Nat Struct Mol Biol. 2021 Mar;28(3):268-277. doi: 10.1038/s41594-020-00556-4. Epub 2021 Feb 15. Nat Struct Mol Biol. 2021. PMID: 33589814 Free PMC article.
Computational design of mechanically coupled axle-rotor protein assemblies.
Courbet A, Hansen J, Hsia Y, Bethel N, Park YJ, Xu C, Moyer A, Boyken SE, Ueda G, Nattermann U, Nagarajan D, Silva DA, Sheffler W, Quispe J, Nord A, King N, Bradley P, Veesler D, Kollman J, Baker D. Courbet A, et al. Science. 2022 Apr 22;376(6591):383-390. doi: 10.1126/science.abm1183. Epub 2022 Apr 21. Science. 2022. PMID: 35446645 Free PMC article.
Management of Post-transplant Infections in Collaborating Hospitals (MATCH) Programme: a prospective cohort of all transplant recipients at Copenhagen University Hospital-Rigshospitalet, Denmark.
Esmann FVL, Zahid S, Moestrup KS, Normand N, Matthews C, Gustafsson F, Sengeløv H, Perch M, Schultz NA, Sørensen SS, Hansen JM, Christensen VB, Murray DD, Lundgren J, Crone CG, Helleberg M. Esmann FVL, et al. Among authors: hansen jm. BMJ Open. 2024 Nov 13;14(11):e089966. doi: 10.1136/bmjopen-2024-089966. BMJ Open. 2024. PMID: 39537569 Free PMC article.
512 results