Melendez V - Search Results

1

Pharmacokinetic evaluation of intravenous artesunate in adults with uncomplicated falciparum malaria in Kenya: a phase II study.

Li Q, Remich S, Miller SR, Ogutu B, Otieno W, Melendez V, Teja-Isavadharm P, Weina PJ, Hickman MR, Smith B, Polhemus M. Li Q, et al. Among authors: melendez v. Malar J. 2014 Jul 22;13:281. doi: 10.1186/1475-2875-13-281. Malar J. 2014. PMID: 25047305 Free PMC article. Clinical Trial.

2

Pharmacokinetic profiles of artesunate after single intravenous doses at 0.5, 1, 2, 4, and 8 mg/kg in healthy volunteers: a phase I study.

Li Q, Cantilena LR, Leary KJ, Saviolakis GA, Miller RS, Melendez V, Weina PJ. Li Q, et al. Among authors: melendez v. Am J Trop Med Hyg. 2009 Oct;81(4):615-21. doi: 10.4269/ajtmh.2009.09-0150. Am J Trop Med Hyg. 2009. PMID: 19815876 Clinical Trial.

3

Pharmacokinetic profiles of artesunate following multiple intravenous doses of 2, 4, and 8 mg/kg in healthy volunteers: phase 1b study.

Miller RS, Li Q, Cantilena LR, Leary KJ, Saviolakis GA, Melendez V, Smith B, Weina PJ. Miller RS, et al. Among authors: melendez v. Malar J. 2012 Aug 1;11:255. doi: 10.1186/1475-2875-11-255. Malar J. 2012. PMID: 22853818 Free PMC article. Clinical Trial.

4

Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections.

Li Q, O'Neil M, Xie L, Caridha D, Zeng Q, Zhang J, Pybus B, Hickman M, Melendez V. Li Q, et al. Among authors: melendez v. Malar J. 2014 Apr 14;13:141. doi: 10.1186/1475-2875-13-141. Malar J. 2014. PMID: 24731238 Free PMC article.

5

Comparison of HPLC with electrochemical detection and LC-MS/MS for the separation and validation of artesunate and dihydroartemisinin in animal and human plasma.

Gu Y, Li Q, Melendez V, Weina P. Gu Y, et al. Among authors: melendez v. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 May 15;867(2):213-8. doi: 10.1016/j.jchromb.2008.04.019. Epub 2008 Apr 20. J Chromatogr B Analyt Technol Biomed Life Sci. 2008. PMID: 18468497

6

A simplified liquid chromatography-mass spectrometry assay for artesunate and dihydroartemisinin, its metabolite, in human plasma.

Teja-Isavadharm P, Siriyanonda D, Siripokasupkul R, Apinan R, Chanarat N, Lim A, Wannaying S, Saunders D, Fukuda MM, Miller RS, Weina PJ, Meléndez V. Teja-Isavadharm P, et al. Among authors: melendez v. Molecules. 2010 Dec 1;15(12):8747-68. doi: 10.3390/molecules15128747. Molecules. 2010. PMID: 21124272 Free PMC article.

7

Formulation and particle size reduction improve bioavailability of poorly water-soluble compounds with antimalarial activity.

Wang H, Li Q, Reyes S, Zhang J, Xie L, Melendez V, Hickman M, Kozar MP. Wang H, et al. Among authors: melendez v. Malar Res Treat. 2013;2013:769234. doi: 10.1155/2013/769234. Epub 2013 May 12. Malar Res Treat. 2013. PMID: 23766925 Free PMC article.

8

Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds.

Marcsisin SR, Sousa JC, Reichard GA, Caridha D, Zeng Q, Roncal N, McNulty R, Careagabarja J, Sciotti RJ, Bennett JW, Zottig VE, Deye G, Li Q, Read L, Hickman M, Dhammika Nanayakkara NP, Walker LA, Smith B, Melendez V, Pybus BS. Marcsisin SR, et al. Among authors: melendez v. Malar J. 2014 Jan 3;13:2. doi: 10.1186/1475-2875-13-2. Malar J. 2014. PMID: 24386891 Free PMC article.

9

Anti-relapse activity of mirincamycin in the Plasmodium cynomolgi sporozoite-infected Rhesus monkey model.

Fracisco S, Teja-isavadharm P, Gettayacamin M, Berman J, Li Q, Melendez V, Saunders D, Xie L, Ohrt C. Fracisco S, et al. Among authors: melendez v. Malar J. 2014 Oct 17;13:409. doi: 10.1186/1475-2875-13-409. Malar J. 2014. PMID: 25326032 Free PMC article.

10

Nanoparticle formulations of decoquinate increase antimalarial efficacy against liver stage Plasmodium infections in mice.

Wang H, Li Q, Reyes S, Zhang J, Zeng Q, Zhang P, Xie L, Lee PJ, Roncal N, Melendez V, Hickman M, Kozar MP. Wang H, et al. Among authors: melendez v. Nanomedicine. 2014 Jan;10(1):57-65. doi: 10.1016/j.nano.2013.07.010. Epub 2013 Jul 25. Nanomedicine. 2014. PMID: 23891618

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