Lambris JD - Search Results

1

Conjugation to albumin-binding molecule tags as a strategy to improve both efficacy and pharmacokinetic properties of the complement inhibitor compstatin.

Huang Y, Reis ES, Knerr PJ, van der Donk WA, Ricklin D, Lambris JD. Huang Y, et al. Among authors: lambris jd. ChemMedChem. 2014 Oct;9(10):2223-6. doi: 10.1002/cmdc.201402212. Epub 2014 Jul 23. ChemMedChem. 2014. PMID: 25056114 Free PMC article.

2

Binding kinetics, structure-activity relationship, and biotransformation of the complement inhibitor compstatin.

Sahu A, Soulika AM, Morikis D, Spruce L, Moore WT, Lambris JD. Sahu A, et al. Among authors: lambris jd. J Immunol. 2000 Sep 1;165(5):2491-9. doi: 10.4049/jimmunol.165.5.2491. J Immunol. 2000. PMID: 10946275

3

Inhibition of heparin/protamine complex-induced complement activation by Compstatin in baboons.

Soulika AM, Khan MM, Hattori T, Bowen FW, Richardson BA, Hack CE, Sahu A, Edmunds LH Jr, Lambris JD. Soulika AM, et al. Among authors: lambris jd. Clin Immunol. 2000 Sep;96(3):212-21. doi: 10.1006/clim.2000.4903. Clin Immunol. 2000. PMID: 10964539 Free article.

4

Studies of structure-activity relations of complement inhibitor compstatin.

Soulika AM, Morikis D, Sarrias MR, Roy M, Spruce LA, Sahu A, Lambris JD. Soulika AM, et al. Among authors: lambris jd. J Immunol. 2003 Aug 15;171(4):1881-90. doi: 10.4049/jimmunol.171.4.1881. J Immunol. 2003. PMID: 12902490

5

Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin.

Katragadda M, Morikis D, Lambris JD. Katragadda M, et al. Among authors: lambris jd. J Biol Chem. 2004 Dec 31;279(53):54987-95. doi: 10.1074/jbc.M409963200. Epub 2004 Oct 15. J Biol Chem. 2004. PMID: 15489226 Free article.

6

Synthetic small-molecule complement inhibitors.

Holland MC, Morikis D, Lambris JD. Holland MC, et al. Among authors: lambris jd. Curr Opin Investig Drugs. 2004 Nov;5(11):1164-73. Curr Opin Investig Drugs. 2004. PMID: 15573867 Review.

7

Compstatin inhibits complement activation by binding to the beta-chain of complement factor 3.

Soulika AM, Holland MC, Sfyroera G, Sahu A, Lambris JD. Soulika AM, et al. Among authors: lambris jd. Mol Immunol. 2006 May;43(12):2023-9. doi: 10.1016/j.molimm.2005.12.002. Epub 2006 Feb 10. Mol Immunol. 2006. PMID: 16472861

8

Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin.

Katragadda M, Magotti P, Sfyroera G, Lambris JD. Katragadda M, et al. Among authors: lambris jd. J Med Chem. 2006 Jul 27;49(15):4616-22. doi: 10.1021/jm0603419. J Med Chem. 2006. PMID: 16854067

9

A structural basis for complement inhibition by Staphylococcus aureus.

Hammel M, Sfyroera G, Ricklin D, Magotti P, Lambris JD, Geisbrecht BV. Hammel M, et al. Among authors: lambris jd. Nat Immunol. 2007 Apr;8(4):430-7. doi: 10.1038/ni1450. Epub 2007 Mar 11. Nat Immunol. 2007. PMID: 17351618

10

Characterization of Ehp, a secreted complement inhibitory protein from Staphylococcus aureus.

Hammel M, Sfyroera G, Pyrpassopoulos S, Ricklin D, Ramyar KX, Pop M, Jin Z, Lambris JD, Geisbrecht BV. Hammel M, et al. Among authors: lambris jd. J Biol Chem. 2007 Oct 12;282(41):30051-61. doi: 10.1074/jbc.M704247200. Epub 2007 Aug 15. J Biol Chem. 2007. PMID: 17699522 Free article.

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