Huang JW - Search Results

1

SHP-1 is a target of regorafenib in colorectal cancer.

Fan LC, Teng HW, Shiau CW, Lin H, Hung MH, Chen YL, Huang JW, Tai WT, Yu HC, Chen KF. Fan LC, et al. Among authors: huang jw. Oncotarget. 2014 Aug 15;5(15):6243-51. doi: 10.18632/oncotarget.2191. Oncotarget. 2014. PMID: 25071018 Free PMC article.

2

Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma.

Tai WT, Cheng AL, Shiau CW, Huang HP, Huang JW, Chen PJ, Chen KF. Tai WT, et al. Among authors: huang jw, huang hp. J Hepatol. 2011 Nov;55(5):1041-8. doi: 10.1016/j.jhep.2011.01.047. Epub 2011 Feb 24. J Hepatol. 2011. PMID: 21354226

3

A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation.

Chen KF, Su JC, Liu CY, Huang JW, Chen KC, Chen WL, Tai WT, Shiau CW. Chen KF, et al. Among authors: huang jw. Cancer Lett. 2012 Aug 1;321(1):27-35. doi: 10.1016/j.canlet.2012.03.023. Epub 2012 Mar 28. Cancer Lett. 2012. PMID: 22465052

4

Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity.

Chen KF, Tai WT, Hsu CY, Huang JW, Liu CY, Chen PJ, Kim I, Shiau CW. Chen KF, et al. Among authors: huang jw. Eur J Med Chem. 2012 Sep;55:220-7. doi: 10.1016/j.ejmech.2012.07.023. Epub 2012 Jul 23. Eur J Med Chem. 2012. PMID: 22871485

5

Synthesis and biological activity of obatoclax derivatives as novel and potent SHP-1 agonists.

Su JC, Chen KF, Chen WL, Liu CY, Huang JW, Tai WT, Chen PJ, Kim I, Shiau CW. Su JC, et al. Among authors: huang jw. Eur J Med Chem. 2012 Oct;56:127-33. doi: 10.1016/j.ejmech.2012.08.024. Epub 2012 Aug 27. Eur J Med Chem. 2012. PMID: 22982119

6

Discovery of novel Src homology region 2 domain-containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma.

Tai WT, Shiau CW, Chen PJ, Chu PY, Huang HP, Liu CY, Huang JW, Chen KF. Tai WT, et al. Among authors: huang jw, huang hp. Hepatology. 2014 Jan;59(1):190-201. doi: 10.1002/hep.26640. Epub 2013 Dec 9. Hepatology. 2014. PMID: 23908138

7

Nintedanib (BIBF-1120) inhibits hepatocellular carcinoma growth independent of angiokinase activity.

Tai WT, Shiau CW, Li YS, Chang CW, Huang JW, Hsueh TT, Yu HC, Chen KF. Tai WT, et al. Among authors: huang jw. J Hepatol. 2014 Jul;61(1):89-97. doi: 10.1016/j.jhep.2014.03.017. Epub 2014 Mar 18. J Hepatol. 2014. PMID: 24657398

8

RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells.

Su JC, Tseng PH, Hsu CY, Tai WT, Huang JW, Ko CH, Lin MW, Liu CY, Chen KF, Shiau CW. Su JC, et al. Among authors: huang jw. Oncotarget. 2014 Jul 15;5(13):4909-19. doi: 10.18632/oncotarget.2054. Oncotarget. 2014. PMID: 24952874 Free PMC article.

9

RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells.

Su JC, Chiang HC, Tseng PH, Tai WT, Hsu CY, Li YS, Huang JW, Ko CH, Lin MW, Chu PY, Liu CY, Chen KF, Shiau CW. Su JC, et al. Among authors: huang jw. Carcinogenesis. 2014 Dec;35(12):2807-14. doi: 10.1093/carcin/bgu210. Epub 2014 Oct 16. Carcinogenesis. 2014. PMID: 25322871

10

Protein tyrosine phosphatase 1B dephosphorylates PITX1 and regulates p120RasGAP in hepatocellular carcinoma.

Tai WT, Chen YL, Chu PY, Chen LJ, Hung MH, Shiau CW, Huang JW, Tsai MH, Chen KF. Tai WT, et al. Among authors: huang jw. Hepatology. 2016 May;63(5):1528-43. doi: 10.1002/hep.28478. Epub 2016 Mar 2. Hepatology. 2016. PMID: 26840794

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