Lun XQ - Search Results

1

Novel MSH6 mutations in treatment-naïve glioblastoma and anaplastic oligodendroglioma contribute to temozolomide resistance independently of MGMT promoter methylation.

Nguyen SA, Stechishin OD, Luchman HA, Lun XQ, Senger DL, Robbins SM, Cairncross JG, Weiss S. Nguyen SA, et al. Among authors: lun xq. Clin Cancer Res. 2014 Sep 15;20(18):4894-903. doi: 10.1158/1078-0432.CCR-13-1856. Epub 2014 Jul 30. Clin Cancer Res. 2014. PMID: 25078279

2

Reovirus as an experimental therapeutic for brain and leptomeningeal metastases from breast cancer.

Yang WQ, Senger DL, Lun XQ, Muzik H, Shi ZQ, Dyck RH, Norman K, Brasher PM, Rewcastle NB, George D, Stewart D, Lee PW, Forsyth PA. Yang WQ, et al. Among authors: lun xq. Gene Ther. 2004 Nov;11(21):1579-89. doi: 10.1038/sj.gt.3302319. Gene Ther. 2004. PMID: 15372068

3

Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates.

Yang WQ, Lun X, Palmer CA, Wilcox ME, Muzik H, Shi ZQ, Dyck R, Coffey M, Thompson B, Hamilton M, Nishikawa SG, Brasher PM, Fonseca K, George D, Rewcastle NB, Johnston RN, Stewart D, Lee PW, Senger DL, Forsyth PA. Yang WQ, et al. Clin Cancer Res. 2004 Dec 15;10(24):8561-76. doi: 10.1158/1078-0432.CCR-04-0940. Clin Cancer Res. 2004. PMID: 15623640

4

Myxoma virus is a novel oncolytic virus with significant antitumor activity against experimental human gliomas.

Lun X, Yang W, Alain T, Shi ZQ, Muzik H, Barrett JW, McFadden G, Bell J, Hamilton MG, Senger DL, Forsyth PA. Lun X, et al. Cancer Res. 2005 Nov 1;65(21):9982-9990. doi: 10.1158/0008-5472.CAN-05-1201. Cancer Res. 2005. PMID: 16267023 Free PMC article.

5

Effects of intravenously administered recombinant vesicular stomatitis virus (VSV(deltaM51)) on multifocal and invasive gliomas.

Lun X, Senger DL, Alain T, Oprea A, Parato K, Stojdl D, Lichty B, Power A, Johnston RN, Hamilton M, Parney I, Bell JC, Forsyth PA. Lun X, et al. J Natl Cancer Inst. 2006 Nov 1;98(21):1546-57. doi: 10.1093/jnci/djj413. J Natl Cancer Inst. 2006. PMID: 17077357

6

Proteolytic disassembly is a critical determinant for reovirus oncolysis.

Alain T, Kim TS, Lun X, Liacini A, Schiff LA, Senger DL, Forsyth PA. Alain T, et al. Mol Ther. 2007 Aug;15(8):1512-21. doi: 10.1038/sj.mt.6300207. Epub 2007 May 22. Mol Ther. 2007. PMID: 17519890 Free PMC article.

7

The p75 neurotrophin receptor is a central regulator of glioma invasion.

Johnston AL, Lun X, Rahn JJ, Liacini A, Wang L, Hamilton MG, Parney IF, Hempstead BL, Robbins SM, Forsyth PA, Senger DL. Johnston AL, et al. PLoS Biol. 2007 Aug;5(8):e212. doi: 10.1371/journal.pbio.0050212. PLoS Biol. 2007. PMID: 17696644 Free PMC article.

8

Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin.

Lun XQ, Zhou H, Alain T, Sun B, Wang L, Barrett JW, Stanford MM, McFadden G, Bell J, Senger DL, Forsyth PA. Lun XQ, et al. Cancer Res. 2007 Sep 15;67(18):8818-27. doi: 10.1158/0008-5472.CAN-07-1214. Cancer Res. 2007. PMID: 17875723 Free PMC article.

9

Oncolytic efficacy of recombinant vesicular stomatitis virus and myxoma virus in experimental models of rhabdoid tumors.

Wu Y, Lun X, Zhou H, Wang L, Sun B, Bell JC, Barrett JW, McFadden G, Biegel JA, Senger DL, Forsyth PA. Wu Y, et al. Clin Cancer Res. 2008 Feb 15;14(4):1218-27. doi: 10.1158/1078-0432.CCR-07-1330. Clin Cancer Res. 2008. PMID: 18281557 Free PMC article.

10

Gamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor.

Wang L, Rahn JJ, Lun X, Sun B, Kelly JJ, Weiss S, Robbins SM, Forsyth PA, Senger DL. Wang L, et al. PLoS Biol. 2008 Nov 25;6(11):e289. doi: 10.1371/journal.pbio.0060289. PLoS Biol. 2008. PMID: 19067488 Free PMC article.

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