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Vaginal delivery of paclitaxel via nanoparticles with non-mucoadhesive surfaces suppresses cervical tumor growth.
Yang M, Yu T, Wang YY, Lai SK, Zeng Q, Miao B, Tang BC, Simons BW, Ensign LM, Liu G, Chan KW, Juang CY, Mert O, Wood J, Fu J, McMahon MT, Wu TC, Hung CF, Hanes J. Yang M, et al. Among authors: yu t. Adv Healthc Mater. 2014 Jul;3(7):1044-52. doi: 10.1002/adhm.201300519. Epub 2013 Dec 16. Adv Healthc Mater. 2014. PMID: 24339398 Free PMC article.
A diaCEST MRI approach for monitoring liposomal accumulation in tumors.
Chan KW, Yu T, Qiao Y, Liu Q, Yang M, Patel H, Liu G, Kinzler KW, Vogelstein B, Bulte JW, van Zijl PC, Hanes J, Zhou S, McMahon MT. Chan KW, et al. Among authors: yu t. J Control Release. 2014 Apr 28;180:51-9. doi: 10.1016/j.jconrel.2014.02.005. Epub 2014 Feb 15. J Control Release. 2014. PMID: 24548481 Free PMC article.
Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI).
Yu T, Chan KW, Anonuevo A, Song X, Schuster BS, Chattopadhyay S, Xu Q, Oskolkov N, Patel H, Ensign LM, van Zjil PC, McMahon MT, Hanes J. Yu T, et al. Nanomedicine. 2015 Feb;11(2):401-5. doi: 10.1016/j.nano.2014.09.019. Epub 2014 Nov 15. Nanomedicine. 2015. PMID: 25461289 Free PMC article.
Use of single-site-functionalized PEG dendrons to prepare gene vectors that penetrate human mucus barriers.
Kim AJ, Boylan NJ, Suk JS, Hwangbo M, Yu T, Schuster BS, Cebotaru L, Lesniak WG, Oh JS, Adstamongkonkul P, Choi AY, Kannan RM, Hanes J. Kim AJ, et al. Among authors: yu t. Angew Chem Int Ed Engl. 2013 Apr 2;52(14):3985-8. doi: 10.1002/anie.201208556. Epub 2013 Mar 4. Angew Chem Int Ed Engl. 2013. PMID: 23460577 Free PMC article. No abstract available.
Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation.
Schneider CS, Xu Q, Boylan NJ, Chisholm J, Tang BC, Schuster BS, Henning A, Ensign LM, Lee E, Adstamongkonkul P, Simons BW, Wang SS, Gong X, Yu T, Boyle MP, Suk JS, Hanes J. Schneider CS, et al. Among authors: yu t. Sci Adv. 2017 Apr 5;3(4):e1601556. doi: 10.1126/sciadv.1601556. eCollection 2017 Apr. Sci Adv. 2017. PMID: 28435870 Free PMC article.
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