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C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.
Mizielinska S, Grönke S, Niccoli T, Ridler CE, Clayton EL, Devoy A, Moens T, Norona FE, Woollacott IOC, Pietrzyk J, Cleverley K, Nicoll AJ, Pickering-Brown S, Dols J, Cabecinha M, Hendrich O, Fratta P, Fisher EMC, Partridge L, Isaacs AM. Mizielinska S, et al. Among authors: cleverley k. Science. 2014 Sep 5;345(6201):1192-1194. doi: 10.1126/science.1256800. Epub 2014 Aug 7. Science. 2014. PMID: 25103406 Free PMC article.
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus.
Granno S, Nixon-Abell J, Berwick DC, Tosh J, Heaton G, Almudimeegh S, Nagda Z, Rain JC, Zanda M, Plagnol V, Tybulewicz VLJ, Cleverley K, Wiseman FK, Fisher EMC, Harvey K. Granno S, et al. Among authors: cleverley k. Sci Rep. 2019 May 13;9(1):7322. doi: 10.1038/s41598-019-43820-4. Sci Rep. 2019. PMID: 31086297 Free PMC article.
Genetic Mapping of APP and Amyloid-β Biology Modulation by Trisomy 21.
Mumford P, Tosh J, Anderle S, Gkanatsiou Wikberg E, Lau G, Noy S, Cleverley K, Saito T, Saido TC, Yu E, Brinkmalm G, Portelius E, Blennow K, Zetterberg H, Tybulewicz V, Fisher EMC, Wiseman FK. Mumford P, et al. Among authors: cleverley k. J Neurosci. 2022 Aug 17;42(33):6453-6468. doi: 10.1523/JNEUROSCI.0521-22.2022. Epub 2022 Jul 14. J Neurosci. 2022. PMID: 35835549 Free PMC article.
The roles of TAF1 in neuroscience and beyond.
Crombie EM, Cleverley K, Timmers HTM, Fisher EMC. Crombie EM, et al. Among authors: cleverley k. R Soc Open Sci. 2024 Sep 25;11(9):240790. doi: 10.1098/rsos.240790. eCollection 2024 Sep. R Soc Open Sci. 2024. PMID: 39323550 Free PMC article. Review.
Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP.
Wiseman FK, Pulford LJ, Barkus C, Liao F, Portelius E, Webb R, Chávez-Gutiérrez L, Cleverley K, Noy S, Sheppard O, Collins T, Powell C, Sarell CJ, Rickman M, Choong X, Tosh JL, Siganporia C, Whittaker HT, Stewart F, Szaruga M; London Down syndrome consortium; Murphy MP, Blennow K, de Strooper B, Zetterberg H, Bannerman D, Holtzman DM, Tybulewicz VLJ, Fisher EMC; LonDownS Consortium. Wiseman FK, et al. Among authors: cleverley k. Brain. 2018 Aug 1;141(8):2457-2474. doi: 10.1093/brain/awy159. Brain. 2018. PMID: 29945247 Free PMC article.
109 results