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Vernakalant activates human cardiac K(2P)17.1 background K(+) channels.
Seyler C, Schweizer PA, Zitron E, Katus HA, Thomas D. Seyler C, et al. Among authors: schweizer pa. Biochem Biophys Res Commun. 2014 Aug 29;451(3):415-20. doi: 10.1016/j.bbrc.2014.07.133. Epub 2014 Aug 7. Biochem Biophys Res Commun. 2014. PMID: 25108155
Carvedilol targets human K2P 3.1 (TASK1) K+ leak channels.
Staudacher K, Staudacher I, Ficker E, Seyler C, Gierten J, Kisselbach J, Rahm AK, Trappe K, Schweizer PA, Becker R, Katus HA, Thomas D. Staudacher K, et al. Among authors: schweizer pa. Br J Pharmacol. 2011 Jul;163(5):1099-110. doi: 10.1111/j.1476-5381.2011.01319.x. Br J Pharmacol. 2011. PMID: 21410455 Free PMC article.
PKC-dependent activation of human K(2P) 18.1 K(+) channels.
Rahm AK, Gierten J, Kisselbach J, Staudacher I, Staudacher K, Schweizer PA, Becker R, Katus HA, Thomas D. Rahm AK, et al. Among authors: schweizer pa. Br J Pharmacol. 2012 May;166(2):764-73. doi: 10.1111/j.1476-5381.2011.01813.x. Br J Pharmacol. 2012. PMID: 22168364 Free PMC article.
147 results