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Carcinogenicity in rats of the SGLT2 inhibitor canagliflozin.
De Jonghe S, Proctor J, Vinken P, Feyen B, Wynant I, Marien D, Geys H, Mamidi RN, Johnson MD. De Jonghe S, et al. Chem Biol Interact. 2014 Dec 5;224:1-12. doi: 10.1016/j.cbi.2014.09.018. Epub 2014 Oct 5. Chem Biol Interact. 2014. PMID: 25289773
Preclinical safety assessment of JNJ-10450232 (NTM-006), a structural analog of acetaminophen, that does not cause hepatotoxicity at supratherapeutic doses.
Zhou J, De Jonghe S, Codd EE, Weiner S, Gallacher D, Stahle P, Kelley MF, Kuffner EK, Flores CM, Eichenbaum GE. Zhou J, et al. Among authors: de jonghe s. Regul Toxicol Pharmacol. 2023 Jan 4:105334. doi: 10.1016/j.yrtph.2023.105334. Online ahead of print. Regul Toxicol Pharmacol. 2023. PMID: 36608923 Free article.
Timing is everything for sperm assessment in fertility studies.
Mariën D, Bailey GP, Eichenbaum G, De Jonghe S. Mariën D, et al. Among authors: de jonghe s. Reprod Toxicol. 2016 Sep;64:141-50. doi: 10.1016/j.reprotox.2016.05.001. Epub 2016 May 12. Reprod Toxicol. 2016. PMID: 27181369
157 results