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High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients.
Derr RS, van Hoesel AQ, Benard A, Goossens-Beumer IJ, Sajet A, Dekker-Ensink NG, de Kruijf EM, Bastiaannet E, Smit VT, van de Velde CJ, Kuppen PJ. Derr RS, et al. Among authors: van hoesel aq. BMC Cancer. 2014 Aug 20;14:604. doi: 10.1186/1471-2407-14-604. BMC Cancer. 2014. PMID: 25139823 Free PMC article.
Age-dependent clinical prognostic value of histone modifications in colorectal cancer.
Goossens-Beumer IJ, Benard A, van Hoesel AQ, Zeestraten EC, Putter H, Böhringer S, Liefers GJ, Morreau H, van de Velde CJ, Kuppen PJ. Goossens-Beumer IJ, et al. Among authors: van hoesel aq. Transl Res. 2015 May;165(5):578-88. doi: 10.1016/j.trsl.2014.11.001. Epub 2014 Nov 13. Transl Res. 2015. PMID: 25488396
Epigenetic silencing of cyclooxygenase-2 affects clinical outcome in gastric cancer.
de Maat MF, van de Velde CJ, Umetani N, de Heer P, Putter H, van Hoesel AQ, Meijer GA, van Grieken NC, Kuppen PJ, Bilchik AJ, Tollenaar RA, Hoon DS. de Maat MF, et al. Among authors: van de velde cj, van hoesel aq, van grieken nc. J Clin Oncol. 2007 Nov 1;25(31):4887-94. doi: 10.1200/JCO.2006.09.8921. J Clin Oncol. 2007. PMID: 17971584 Clinical Trial.
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