Wright MB - Search Results

1

Minireview: Challenges and opportunities in development of PPAR agonists.

Wright MB, Bortolini M, Tadayyon M, Bopst M. Wright MB, et al. Mol Endocrinol. 2014 Nov;28(11):1756-68. doi: 10.1210/me.2013-1427. Epub 2014 Aug 22. Mol Endocrinol. 2014. PMID: 25148456 Free PMC article. Review.

2

Examining the safety of PPAR agonists - current trends and future prospects.

Bortolini M, Wright MB, Bopst M, Balas B. Bortolini M, et al. Among authors: wright mb. Expert Opin Drug Saf. 2013 Jan;12(1):65-79. doi: 10.1517/14740338.2013.741585. Epub 2012 Nov 8. Expert Opin Drug Saf. 2013. PMID: 23134541 Review.

3

Effects of peroxisome proliferator activated receptors (PPAR)-γ and -α agonists on cochlear protection from oxidative stress.

Sekulic-Jablanovic M, Petkovic V, Wright MB, Kucharava K, Huerzeler N, Levano S, Brand Y, Leitmeyer K, Glutz A, Bausch A, Bodmer D. Sekulic-Jablanovic M, et al. Among authors: wright mb. PLoS One. 2017 Nov 28;12(11):e0188596. doi: 10.1371/journal.pone.0188596. eCollection 2017. PLoS One. 2017. PMID: 29182629 Free PMC article.

4

Comparative molecular profiling of the PPARα/γ activator aleglitazar: PPAR selectivity, activity and interaction with cofactors.

Dietz M, Mohr P, Kuhn B, Maerki HP, Hartman P, Ruf A, Benz J, Grether U, Wright MB. Dietz M, et al. Among authors: wright mb. ChemMedChem. 2012 Jun;7(6):1101-11. doi: 10.1002/cmdc.201100598. Epub 2012 Apr 4. ChemMedChem. 2012. PMID: 22489042 Free PMC article.

5

New Insights on the mechanism of PPAR-targeted drugs.

Grether U, Klaus W, Kuhn B, Maerki HP, Mohr P, Wright MB. Grether U, et al. Among authors: wright mb. ChemMedChem. 2010 Dec 3;5(12):1973-6. doi: 10.1002/cmdc.201000446. ChemMedChem. 2010. PMID: 21069658 No abstract available.

6

Effects of the dual PPAR-α/γ agonist aleglitazar on glycaemic control and organ protection in the Zucker diabetic fatty rat.

Bénardeau A, Verry P, Atzpodien EA, Funk JM, Meyer M, Mizrahi J, Winter M, Wright MB, Uhles S, Sebokova E. Bénardeau A, et al. Among authors: wright mb. Diabetes Obes Metab. 2013 Feb;15(2):164-74. doi: 10.1111/dom.12006. Epub 2012 Oct 3. Diabetes Obes Metab. 2013. PMID: 22958363

7

Therapeutic potential of the dual peroxisome proliferator activated receptor (PPAR)α/γ agonist aleglitazar in attenuating TNF-α-mediated inflammation and insulin resistance in human adipocytes.

Massaro M, Scoditti E, Pellegrino M, Carluccio MA, Calabriso N, Wabitsch M, Storelli C, Wright M, De Caterina R. Massaro M, et al. Pharmacol Res. 2016 May;107:125-136. doi: 10.1016/j.phrs.2016.02.027. Epub 2016 Mar 11. Pharmacol Res. 2016. PMID: 26976796

8

Recent progress in liver X receptor-selective modulators.

Ratni H, Wright MB. Ratni H, et al. Among authors: wright mb. Curr Opin Drug Discov Devel. 2010 Jul;13(4):403-13. Curr Opin Drug Discov Devel. 2010. PMID: 20597026 Review.

9

Combination treatment with pioglitazone and fenofibrate attenuates pioglitazone-mediated acceleration of bone loss in ovariectomized rats.

Samadfam R, Awori M, Bénardeau A, Bauss F, Sebokova E, Wright M, Smith SY. Samadfam R, et al. J Endocrinol. 2012 Feb;212(2):179-86. doi: 10.1530/JOE-11-0356. Epub 2011 Nov 7. J Endocrinol. 2012. PMID: 22062085

10

Comparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytes.

Deehan R, Maerz-Weiss P, Catlett NL, Steiner G, Wong B, Wright MB, Blander G, Elliston KO, Ladd W, Bobadilla M, Mizrahi J, Haefliger C, Edgar A. Deehan R, et al. Among authors: wright mb. PLoS One. 2012;7(4):e35012. doi: 10.1371/journal.pone.0035012. Epub 2012 Apr 13. PLoS One. 2012. PMID: 22514701 Free PMC article.

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