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Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan.
Driessen NN, Stoop EJM, Ummels R, Gurcha SS, Mishra AK, Larrouy-Maumus G, Nigou J, Gilleron M, Puzo G, Maaskant JJ, Sparrius M, Besra GS, Bitter W, Vandenbroucke-Grauls CMJE, Appelmelk BJ. Driessen NN, et al. Among authors: ummels r. Microbiology (Reading). 2010 Nov;156(Pt 11):3492-3502. doi: 10.1099/mic.0.037507-0. Epub 2010 Aug 5. Microbiology (Reading). 2010. PMID: 20688818 Free PMC article.
Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway.
Daleke MH, Cascioferro A, de Punder K, Ummels R, Abdallah AM, van der Wel N, Peters PJ, Luirink J, Manganelli R, Bitter W. Daleke MH, et al. Among authors: ummels r. J Biol Chem. 2011 May 27;286(21):19024-34. doi: 10.1074/jbc.M110.204966. Epub 2011 Apr 6. J Biol Chem. 2011. PMID: 21471225 Free PMC article.
General secretion signal for the mycobacterial type VII secretion pathway.
Daleke MH, Ummels R, Bawono P, Heringa J, Vandenbroucke-Grauls CM, Luirink J, Bitter W. Daleke MH, et al. Among authors: ummels r. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11342-7. doi: 10.1073/pnas.1119453109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733768 Free PMC article.
Specific chaperones for the type VII protein secretion pathway.
Daleke MH, van der Woude AD, Parret AH, Ummels R, de Groot AM, Watson D, Piersma SR, Jiménez CR, Luirink J, Bitter W, Houben EN. Daleke MH, et al. Among authors: ummels r. J Biol Chem. 2012 Sep 14;287(38):31939-47. doi: 10.1074/jbc.M112.397596. Epub 2012 Jul 29. J Biol Chem. 2012. PMID: 22843727 Free PMC article.
Composition of the type VII secretion system membrane complex.
Houben EN, Bestebroer J, Ummels R, Wilson L, Piersma SR, Jiménez CR, Ottenhoff TH, Luirink J, Bitter W. Houben EN, et al. Among authors: ummels r. Mol Microbiol. 2012 Oct;86(2):472-84. doi: 10.1111/j.1365-2958.2012.08206.x. Epub 2012 Aug 27. Mol Microbiol. 2012. PMID: 22925462 Free article.
Differential detergent extraction of mycobacterium marinum cell envelope proteins identifies an extensively modified threonine-rich outer membrane protein with channel activity.
van der Woude AD, Mahendran KR, Ummels R, Piersma SR, Pham TV, Jiménez CR, de Punder K, van der Wel NN, Winterhalter M, Luirink J, Bitter W, Houben EN. van der Woude AD, et al. Among authors: ummels r. J Bacteriol. 2013 May;195(9):2050-9. doi: 10.1128/JB.02236-12. Epub 2013 Mar 1. J Bacteriol. 2013. PMID: 23457249 Free PMC article.
Analysis of SecA2-dependent substrates in Mycobacterium marinum identifies protein kinase G (PknG) as a virulence effector.
van der Woude AD, Stoop EJ, Stiess M, Wang S, Ummels R, van Stempvoort G, Piersma SR, Cascioferro A, Jiménez CR, Houben EN, Luirink J, Pieters J, van der Sar AM, Bitter W. van der Woude AD, et al. Among authors: ummels r. Cell Microbiol. 2014 Feb;16(2):280-95. doi: 10.1111/cmi.12221. Epub 2013 Nov 6. Cell Microbiol. 2014. PMID: 24119166
40 results