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Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.
Mekhdjian AH, Kai F, Rubashkin MG, Prahl LS, Przybyla LM, McGregor AL, Bell ES, Barnes JM, DuFort CC, Ou G, Chang AC, Cassereau L, Tan SJ, Pickup MW, Lakins JN, Ye X, Davidson MW, Lammerding J, Odde DJ, Dunn AR, Weaver VM. Mekhdjian AH, et al. Among authors: davidson mw. Mol Biol Cell. 2017 Jun 1;28(11):1467-1488. doi: 10.1091/mbc.E16-09-0654. Epub 2017 Apr 5. Mol Biol Cell. 2017. PMID: 28381423 Free PMC article.
The cancer glycocalyx mechanically primes integrin-mediated growth and survival.
Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L, Rubashkin MG, Magbanua MJ, Thorn KS, Davidson MW, Rugo HS, Park JW, Hammer DA, Giannone G, Bertozzi CR, Weaver VM. Paszek MJ, et al. Among authors: davidson mw. Nature. 2014 Jul 17;511(7509):319-25. doi: 10.1038/nature13535. Epub 2014 Jun 25. Nature. 2014. PMID: 25030168 Free PMC article.
A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells.
Burnette DT, Shao L, Ott C, Pasapera AM, Fischer RS, Baird MA, Der Loughian C, Delanoe-Ayari H, Paszek MJ, Davidson MW, Betzig E, Lippincott-Schwartz J. Burnette DT, et al. Among authors: davidson mw. J Cell Biol. 2014 Apr 14;205(1):83-96. doi: 10.1083/jcb.201311104. Epub 2014 Apr 7. J Cell Biol. 2014. PMID: 24711500 Free PMC article.
Talin determines the nanoscale architecture of focal adhesions.
Liu J, Wang Y, Goh WI, Goh H, Baird MA, Ruehland S, Teo S, Bate N, Critchley DR, Davidson MW, Kanchanawong P. Liu J, et al. Among authors: davidson mw. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4864-73. doi: 10.1073/pnas.1512025112. Epub 2015 Aug 17. Proc Natl Acad Sci U S A. 2015. PMID: 26283369 Free PMC article.
162 results