Othersen O - Search Results

1

Difluoro-dioxolo-benzoimidazol-benzamides as potent inhibitors of CK1δ and ε with nanomolar inhibitory activity on cancer cell proliferation.

Richter J, Bischof J, Zaja M, Kohlhof H, Othersen O, Vitt D, Alscher V, Pospiech I, García-Reyes B, Berg S, Leban J, Knippschild U. Richter J, et al. Among authors: othersen o. J Med Chem. 2014 Oct 9;57(19):7933-46. doi: 10.1021/jm500600b. Epub 2014 Sep 17. J Med Chem. 2014. PMID: 25191940

2

2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1δ/ε.

Bischof J, Leban J, Zaja M, Grothey A, Radunsky B, Othersen O, Strobl S, Vitt D, Knippschild U. Bischof J, et al. Among authors: othersen o. Amino Acids. 2012 Oct;43(4):1577-91. doi: 10.1007/s00726-012-1234-x. Epub 2012 Feb 14. Amino Acids. 2012. PMID: 22331384 Free PMC article.

3

Structural changes and binding characteristics of the tetracycline-repressor binding site on induction.

Lanig H, Othersen OG, Seidel U, Beierlein FR, Exner TE, Clark T. Lanig H, et al. Among authors: othersen og. J Med Chem. 2006 Jun 15;49(12):3444-7. doi: 10.1021/jm060289g. J Med Chem. 2006. PMID: 16759085

4

Systematic surface scan of the most favorable interaction sites of magnesium ions with tetracycline.

Othersen OG, Lanig H, Clark T. Othersen OG, et al. J Med Chem. 2003 Dec 18;46(26):5571-4. doi: 10.1021/jm034199c. J Med Chem. 2003. PMID: 14667210

5

The structure of 5a,6-anhydrotetracycline and its Mg2+ complexes in aqueous solution.

Othersen OG, Lanig H, Clark T. Othersen OG, et al. J Mol Model. 2006 Sep;12(6):953-63. doi: 10.1007/s00894-005-0055-1. Epub 2006 May 3. J Mol Model. 2006. PMID: 16670875

6

Molecular dynamics simulations of the tetracycline-repressor protein: the mechanism of induction.

Lanig H, Othersen OG, Beierlein FR, Seidel U, Clark T. Lanig H, et al. Among authors: othersen og. J Mol Biol. 2006 Jun 16;359(4):1125-36. doi: 10.1016/j.jmb.2006.04.014. Epub 2006 Apr 27. J Mol Biol. 2006. PMID: 16690082

7

SCRF-DFT and NMR comparison of tetracycline and 5a,6-anhydrotetracycline in solution.

Othersen OG, Waibel R, Lanig H, Gmeiner P, Clark T. Othersen OG, et al. J Phys Chem B. 2006 Dec 7;110(48):24766-74. doi: 10.1021/jp064457s. J Phys Chem B. 2006. PMID: 17134242

8

Molecular dynamics characterization of the structures and induction mechanisms of a reverse phenotype of the tetracycline receptor.

Seidel U, Othersen OG, Haberl F, Lanig H, Beierlein FR, Clark T. Seidel U, et al. Among authors: othersen og. J Phys Chem B. 2007 May 31;111(21):6006-14. doi: 10.1021/jp0674468. Epub 2007 May 5. J Phys Chem B. 2007. PMID: 17480066

9

Simulating FRET from tryptophan: is the rotamer model correct?

Beierlein FR, Othersen OG, Lanig H, Schneider S, Clark T. Beierlein FR, et al. Among authors: othersen og. J Am Chem Soc. 2006 Apr 19;128(15):5142-52. doi: 10.1021/ja058414l. J Am Chem Soc. 2006. PMID: 16608350

10

Monitoring biological membrane-potential changes: a CI QM/MM study.

Rusu CF, Lanig H, Othersen OG, Kryschi C, Clark T. Rusu CF, et al. Among authors: othersen og. J Phys Chem B. 2008 Feb 28;112(8):2445-55. doi: 10.1021/jp075372+. Epub 2008 Feb 5. J Phys Chem B. 2008. PMID: 18247593

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