Malladi SS - Search Results

1

Determinants of activity at human Toll-like receptors 7 and 8: quantitative structure-activity relationship (QSAR) of diverse heterocyclic scaffolds.

Yoo E, Salunke DB, Sil D, Guo X, Salyer AC, Hermanson AR, Kumar M, Malladi SS, Balakrishna R, Thompson WH, Tanji H, Ohto U, Shimizu T, David SA. Yoo E, et al. Among authors: malladi ss. J Med Chem. 2014 Oct 9;57(19):7955-70. doi: 10.1021/jm500744f. Epub 2014 Sep 17. J Med Chem. 2014. PMID: 25192394 Free PMC article.

2

Structure-activity relationships of lipopolysaccharide sequestration in guanylhydrazone-bearing lipopolyamines.

Wu W, Sil D, Szostak ML, Malladi SS, Warshakoon HJ, Kimbrell MR, Cromer JR, David SA. Wu W, et al. Among authors: malladi ss. Bioorg Med Chem. 2009 Jan 15;17(2):709-15. doi: 10.1016/j.bmc.2008.11.051. Epub 2008 Nov 24. Bioorg Med Chem. 2009. PMID: 19064323 Free PMC article.

3

Regioisomerism-dependent TLR7 agonism and antagonism in an imidazoquinoline.

Shukla NM, Kimbrell MR, Malladi SS, David SA. Shukla NM, et al. Among authors: malladi ss. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2211-4. doi: 10.1016/j.bmcl.2009.02.100. Epub 2009 Feb 28. Bioorg Med Chem Lett. 2009. PMID: 19285861

4

Structure-activity relationships of lipopolysaccharide sequestration in N-alkylpolyamines.

Shrestha A, Sil D, Malladi SS, Warshakoon HJ, David SA. Shrestha A, et al. Among authors: malladi ss. Bioorg Med Chem Lett. 2009 May 1;19(9):2478-81. doi: 10.1016/j.bmcl.2009.03.055. Epub 2009 Mar 18. Bioorg Med Chem Lett. 2009. PMID: 19332373 Free PMC article.

5

Structure-activity relationships in toll-like receptor-2 agonistic diacylthioglycerol lipopeptides.

Wu W, Li R, Malladi SS, Warshakoon HJ, Kimbrell MR, Amolins MW, Ukani R, Datta A, David SA. Wu W, et al. Among authors: malladi ss. J Med Chem. 2010 Apr 22;53(8):3198-213. doi: 10.1021/jm901839g. J Med Chem. 2010. PMID: 20302301 Free PMC article.

6

Structure-activity relationships in human toll-like receptor 7-active imidazoquinoline analogues.

Shukla NM, Malladi SS, Mutz CA, Balakrishna R, David SA. Shukla NM, et al. Among authors: malladi ss. J Med Chem. 2010 Jun 10;53(11):4450-65. doi: 10.1021/jm100358c. J Med Chem. 2010. PMID: 20481492 Free PMC article.

7

Structure-activity relationships in nucleotide oligomerization domain 1 (Nod1) agonistic γ-glutamyldiaminopimelic acid derivatives.

Agnihotri G, Ukani R, Malladi SS, Warshakoon HJ, Balakrishna R, Wang X, David SA. Agnihotri G, et al. Among authors: malladi ss. J Med Chem. 2011 Mar 10;54(5):1490-510. doi: 10.1021/jm101535e. Epub 2011 Feb 7. J Med Chem. 2011. PMID: 21299227 Free PMC article.

8

Preliminary evaluation of a 3H imidazoquinoline library as dual TLR7/TLR8 antagonists.

Shukla NM, Malladi SS, Day V, David SA. Shukla NM, et al. Among authors: malladi ss. Bioorg Med Chem. 2011 Jun 15;19(12):3801-11. doi: 10.1016/j.bmc.2011.04.052. Epub 2011 May 1. Bioorg Med Chem. 2011. PMID: 21620714 Free PMC article.

9

Structure-activity relationships in toll-like receptor 2-agonists leading to simplified monoacyl lipopeptides.

Agnihotri G, Crall BM, Lewis TC, Day TP, Balakrishna R, Warshakoon HJ, Malladi SS, David SA. Agnihotri G, et al. Among authors: malladi ss. J Med Chem. 2011 Dec 8;54(23):8148-60. doi: 10.1021/jm201071e. Epub 2011 Nov 4. J Med Chem. 2011. PMID: 22007676 Free PMC article.

10

Toll-like receptor (TLR)-7 and -8 modulatory activities of dimeric imidazoquinolines.

Shukla NM, Mutz CA, Malladi SS, Warshakoon HJ, Balakrishna R, David SA. Shukla NM, et al. Among authors: malladi ss. J Med Chem. 2012 Feb 9;55(3):1106-16. doi: 10.1021/jm2010207. Epub 2012 Jan 27. J Med Chem. 2012. PMID: 22239408 Free PMC article.

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