Moll U - Search Results

1

UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib.

Landmann H, Proia DA, He S, Ogawa LS, Kramer F, Beißbarth T, Grade M, Gaedcke J, Ghadimi M, Moll U, Dobbelstein M. Landmann H, et al. Among authors: moll u. Cell Death Dis. 2014 Sep 11;5(9):e1411. doi: 10.1038/cddis.2014.378. Cell Death Dis. 2014. PMID: 25210794 Free PMC article.

2

HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates.

Schulz R, Dobbelstein M, Moll UM. Schulz R, et al. Oncoimmunology. 2012 Nov 1;1(8):1425-1426. doi: 10.4161/onci.21173. Oncoimmunology. 2012. PMID: 23243616 Free PMC article.

3

MicroRNA-101 Suppresses Tumor Cell Proliferation by Acting as an Endogenous Proteasome Inhibitor via Targeting the Proteasome Assembly Factor POMP.

Zhang X, Schulz R, Edmunds S, Krüger E, Markert E, Gaedcke J, Cormet-Boyaka E, Ghadimi M, Beissbarth T, Levine AJ, Moll UM, Dobbelstein M. Zhang X, et al. Mol Cell. 2015 Jul 16;59(2):243-57. doi: 10.1016/j.molcel.2015.05.036. Epub 2015 Jul 2. Mol Cell. 2015. PMID: 26145175 Free article.

4

Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.

Kramer D, Stark N, Schulz-Heddergott R, Erytch N, Edmunds S, Roßmann L, Bastians H, Concin N, Moll UM, Dobbelstein M. Kramer D, et al. Cell Death Differ. 2017 Feb;24(2):300-316. doi: 10.1038/cdd.2016.124. Epub 2016 Nov 11. Cell Death Differ. 2017. PMID: 27834954 Free PMC article.

5

HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer.

Schulz R, Streller F, Scheel AH, Rüschoff J, Reinert MC, Dobbelstein M, Marchenko ND, Moll UM. Schulz R, et al. Among authors: moll um. Cell Death Dis. 2014 Jan 2;5(1):e980. doi: 10.1038/cddis.2013.508. Cell Death Dis. 2014. PMID: 24384723 Free PMC article.

6

Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment.

Alexandrova EM, Yallowitz AR, Li D, Xu S, Schulz R, Proia DA, Lozano G, Dobbelstein M, Moll UM. Alexandrova EM, et al. Among authors: moll um. Nature. 2015 Jul 16;523(7560):352-6. doi: 10.1038/nature14430. Epub 2015 May 25. Nature. 2015. PMID: 26009011 Free PMC article.

7

Targeting tumour-supportive cellular machineries in anticancer drug development.

Dobbelstein M, Moll U. Dobbelstein M, et al. Among authors: moll u. Nat Rev Drug Discov. 2014 Mar;13(3):179-96. doi: 10.1038/nrd4201. Nat Rev Drug Discov. 2014. PMID: 24577400 Review.

8

Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression.

Schulz R, Marchenko ND, Holembowski L, Fingerle-Rowson G, Pesic M, Zender L, Dobbelstein M, Moll UM. Schulz R, et al. J Exp Med. 2012 Feb 13;209(2):275-89. doi: 10.1084/jem.20111117. Epub 2012 Jan 23. J Exp Med. 2012. PMID: 22271573 Free PMC article.

9

Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes.

Beyer U, Moll-Rocek J, Moll UM, Dobbelstein M. Beyer U, et al. Among authors: moll um, moll rocek j. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3624-9. doi: 10.1073/pnas.1016201108. Epub 2011 Feb 7. Proc Natl Acad Sci U S A. 2011. PMID: 21300884 Free PMC article.

10

Mdm2 as a chromatin modifier.

Wienken M, Moll UM, Dobbelstein M. Wienken M, et al. J Mol Cell Biol. 2017 Feb 1;9(1):74-80. doi: 10.1093/jmcb/mjw046. J Mol Cell Biol. 2017. PMID: 27927750 Free PMC article. Review.

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