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HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.
Heap GA, Weedon MN, Bewshea CM, Singh A, Chen M, Satchwell JB, Vivian JP, So K, Dubois PC, Andrews JM, Annese V, Bampton P, Barnardo M, Bell S, Cole A, Connor SJ, Creed T, Cummings FR, D'Amato M, Daneshmend TK, Fedorak RN, Florin TH, Gaya DR, Greig E, Halfvarson J, Hart A, Irving PM, Jones G, Karban A, Lawrance IC, Lee JC, Lees C, Lev-Tzion R, Lindsay JO, Mansfield J, Mawdsley J, Mazhar Z, Parkes M, Parnell K, Orchard TR, Radford-Smith G, Russell RK, Reffitt D, Satsangi J, Silverberg MS, Sturniolo GC, Tremelling M, Tsianos EV, van Heel DA, Walsh A, Watermeyer G, Weersma RK, Zeissig S, Rossjohn J, Holden AL; International Serious Adverse Events Consortium; IBD Pharmacogenetics Study Group; Ahmad T. Heap GA, et al. Nat Genet. 2014 Oct;46(10):1131-4. doi: 10.1038/ng.3093. Epub 2014 Sep 14. Nat Genet. 2014. PMID: 25217962 Free PMC article.
Validation of predictive models for disease outcomes in paediatric ulcerative colitis: A multicentre prospective inception cohort.
Atia O, Klomberg RCW, de Ridder L, Kemos P, Ruemmele FM, Kang B, Choi S, Choe BH, Kang Y, Shouval DS, Focht G, Ledder O, Lev-Tzion R, Carmon N, Berger TD, Turner D, Croft NM, Orlanski-Meyer E. Atia O, et al. Aliment Pharmacol Ther. 2023 Jul;58(2):182-190. doi: 10.1111/apt.17544. Epub 2023 May 29. Aliment Pharmacol Ther. 2023. PMID: 37248642
Children included in randomised controlled trials of biologics in inflammatory bowel diseases do not represent the real-world patient mix.
Atia O, Pujol-Muncunill G, Navas-López VM, Orlanski-Meyer E, Ledder O, Lev-Tzion R, Focht G, Shteyer E, Stein R, Aloi M, Russell RK, Martin-de-Carpi J, Turner D. Atia O, et al. Aliment Pharmacol Ther. 2022 Sep;56(5):794-801. doi: 10.1111/apt.17092. Epub 2022 Jun 23. Aliment Pharmacol Ther. 2022. PMID: 35735987 Free PMC article.
Infliximab in young paediatric IBD patients: it is all about the dosing.
Jongsma MME, Winter DA, Huynh HQ, Norsa L, Hussey S, Kolho KL, Bronsky J, Assa A, Cohen S, Lev-Tzion R, Van Biervliet S, Rizopoulos D, de Meij TGJ, Shouval DS, Wine E, Wolters VM, Martinez-Vinson C, de Ridder L; Paediatric IBD Porto Group of ESPGHAN. Jongsma MME, et al. Eur J Pediatr. 2020 Dec;179(12):1935-1944. doi: 10.1007/s00431-020-03750-0. Epub 2020 Aug 19. Eur J Pediatr. 2020. PMID: 32813123 Free PMC article.
36 results