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Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.
Fares I, Chagraoui J, Gareau Y, Gingras S, Ruel R, Mayotte N, Csaszar E, Knapp DJ, Miller P, Ngom M, Imren S, Roy DC, Watts KL, Kiem HP, Herrington R, Iscove NN, Humphries RK, Eaves CJ, Cohen S, Marinier A, Zandstra PW, Sauvageau G. Fares I, et al. Among authors: gingras s. Science. 2014 Sep 19;345(6203):1509-12. doi: 10.1126/science.1256337. Science. 2014. PMID: 25237102 Free PMC article.
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.
Baccelli I, Gareau Y, Lehnertz B, Gingras S, Spinella JF, Corneau S, Mayotte N, Girard S, Frechette M, Blouin-Chagnon V, Leveillé K, Boivin I, MacRae T, Krosl J, Thiollier C, Lavallée VP, Kanshin E, Bertomeu T, Coulombe-Huntington J, St-Denis C, Bordeleau ME, Boucher G, Roux PP, Lemieux S, Tyers M, Thibault P, Hébert J, Marinier A, Sauvageau G. Baccelli I, et al. Among authors: gingras s. Cancer Cell. 2019 Jul 8;36(1):84-99.e8. doi: 10.1016/j.ccell.2019.06.003. Cancer Cell. 2019. PMID: 31287994 Free article.
Dysfunction of exhausted T cells is enforced by MCT11-mediated lactate metabolism.
Peralta RM, Xie B, Lontos K, Nieves-Rosado H, Spahr K, Joshi S, Ford BR, Quann K, Frisch AT, Dean V, Philbin M, Cillo AR, Gingras S, Poholek AC, Kane LP, Rivadeneira DB, Delgoffe GM. Peralta RM, et al. Among authors: gingras s. Nat Immunol. 2024 Dec;25(12):2297-2307. doi: 10.1038/s41590-024-01999-3. Epub 2024 Nov 8. Nat Immunol. 2024. PMID: 39516648 Free PMC article.
Influence of proteolytic cleavage of ENaC's γ subunit upon Na+ and K+ handling.
Ray EC, Nickerson A, Sheng S, Carrisoza-Gaytan R, Lam T, Marciszyn A, Zhang L, Jordahl A, Bi C, Winfrey A, Kou Z, Gingras S, Kirabo A, Satlin LM, Kleyman TR. Ray EC, et al. Among authors: gingras s. Am J Physiol Renal Physiol. 2024 Jun 1;326(6):F1066-F1077. doi: 10.1152/ajprenal.00027.2024. Epub 2024 Apr 18. Am J Physiol Renal Physiol. 2024. PMID: 38634134
Retraction Note: Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins.
Martinez J, Subbarao Malireddi RK, Lu Q, Cunha LD, Pelletier S, Gingras S, Orchard R, Guan JL, Tan H, Peng J, Kanneganti TD, Virgin HW, Green DR. Martinez J, et al. Among authors: gingras s. Nat Cell Biol. 2024 Apr;26(4):660. doi: 10.1038/s41556-024-01383-1. Nat Cell Biol. 2024. PMID: 38438803 Free PMC article. No abstract available.
152 results