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An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann SM, Krüger C, Park B, Derkow K, Rosenberger K, Baumgart J, Trimbuch T, Eom G, Hinz M, Kaul D, Habbel P, Kälin R, Franzoni E, Rybak A, Nguyen D, Veh R, Ninnemann O, Peters O, Nitsch R, Heppner FL, Golenbock D, Schott E, Ploegh HL, Wulczyn FG, Lehnardt S. Lehmann SM, et al. Among authors: rosenberger k. Nat Neurosci. 2012 Jun;15(6):827-35. doi: 10.1038/nn.3113. Nat Neurosci. 2012. PMID: 22610069
Elevation in type I interferons inhibits HCN1 and slows cortical neuronal oscillations.
Stadler K, Bierwirth C, Stoenica L, Battefeld A, Reetz O, Mix E, Schuchmann S, Velmans T, Rosenberger K, Bräuer AU, Lehnardt S, Nitsch R, Budt M, Wolff T, Kole MH, Strauss U. Stadler K, et al. Among authors: rosenberger k. Cereb Cortex. 2014 Jan;24(1):199-210. doi: 10.1093/cercor/bhs305. Epub 2012 Oct 4. Cereb Cortex. 2014. PMID: 23042740
MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4.
Walsh JT, Hendrix S, Boato F, Smirnov I, Zheng J, Lukens JR, Gadani S, Hechler D, Gölz G, Rosenberger K, Kammertöns T, Vogt J, Vogelaar C, Siffrin V, Radjavi A, Fernandez-Castaneda A, Gaultier A, Gold R, Kanneganti TD, Nitsch R, Zipp F, Kipnis J. Walsh JT, et al. Among authors: rosenberger k. J Clin Invest. 2015 Feb;125(2):699-714. doi: 10.1172/JCI76210. Epub 2015 Jan 20. J Clin Invest. 2015. PMID: 25607842 Free PMC article.
MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4.
Walsh JT, Hendrix S, Boato F, Smirnov I, Zheng J, Lukens JR, Gadani S, Hechler D, Gölz G, Rosenberger K, Kammertöns T, Vogt J, Vogelaar C, Siffrin V, Radjavi A, Fernandez-Castaneda A, Gaultier A, Gold R, Kanneganti TD, Nitsch R, Zipp F, Kipnis J. Walsh JT, et al. Among authors: rosenberger k. J Clin Invest. 2015 Jun;125(6):2547. doi: 10.1172/JCI82458. Epub 2015 May 4. J Clin Invest. 2015. PMID: 25938785 Free PMC article. No abstract available.
85 results