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Page 1
Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni.
Partridge FA, Bataille CJR, Forman R, Marriott AE, Forde-Thomas J, Häberli C, Dinsdale RL, O'Sullivan JDB, Willis NJ, Wynne GM, Whiteland H, Archer J, Steven A, Keiser J, Turner JD, Hoffmann KF, Taylor MJ, Else KJ, Russell AJ, Sattelle DB. Partridge FA, et al. Among authors: sattelle db. ACS Infect Dis. 2021 May 14;7(5):1260-1274. doi: 10.1021/acsinfecdis.1c00025. Epub 2021 Apr 2. ACS Infect Dis. 2021. PMID: 33797218 Free PMC article.
Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo.
Partridge FA, Murphy EA, Willis NJ, Bataille CJ, Forman R, Heyer-Chauhan N, Marinič B, Sowood DJ, Wynne GM, Else KJ, Russell AJ, Sattelle DB. Partridge FA, et al. Among authors: sattelle db. PLoS Negl Trop Dis. 2017 Feb 9;11(2):e0005359. doi: 10.1371/journal.pntd.0005359. eCollection 2017 Feb. PLoS Negl Trop Dis. 2017. PMID: 28182663 Free PMC article.
2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm.
Partridge FA, Forman R, Willis NJ, Bataille CJR, Murphy EA, Brown AE, Heyer-Chauhan N, Marinič B, Sowood DJC, Wynne GM, Else KJ, Russell AJ, Sattelle DB. Partridge FA, et al. Among authors: sattelle db. PLoS Negl Trop Dis. 2018 Jul 11;12(7):e0006487. doi: 10.1371/journal.pntd.0006487. eCollection 2018 Jul. PLoS Negl Trop Dis. 2018. PMID: 29995893 Free PMC article.
An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.
Partridge FA, Brown AE, Buckingham SD, Willis NJ, Wynne GM, Forman R, Else KJ, Morrison AA, Matthews JB, Russell AJ, Lomas DA, Sattelle DB. Partridge FA, et al. Among authors: sattelle db. Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):8-21. doi: 10.1016/j.ijpddr.2017.11.004. Epub 2017 Dec 2. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29223747 Free PMC article.
Whipworm and roundworm infections.
Else KJ, Keiser J, Holland CV, Grencis RK, Sattelle DB, Fujiwara RT, Bueno LL, Asaolu SO, Sowemimo OA, Cooper PJ. Else KJ, et al. Among authors: sattelle db. Nat Rev Dis Primers. 2020 May 28;6(1):44. doi: 10.1038/s41572-020-0171-3. Nat Rev Dis Primers. 2020. PMID: 32467581 Review.
The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease.
Furutani S, Ihara M, Lees K, Buckingham SD, Partridge FA, David JA, Patel R, Warchal S, Mellor IR, Matsuda K, Sattelle DB. Furutani S, et al. Among authors: sattelle db. Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):350-360. doi: 10.1016/j.ijpddr.2018.06.001. Epub 2018 Jun 4. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29957333 Free PMC article.
Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance.
Buckingham SD, Partridge FA, Poulton BC, Miller BS, McKendry RA, Lycett GJ, Sattelle DB. Buckingham SD, et al. Among authors: sattelle db. PLoS Negl Trop Dis. 2021 Jun 3;15(6):e0008639. doi: 10.1371/journal.pntd.0008639. eCollection 2021 Jun. PLoS Negl Trop Dis. 2021. PMID: 34081710 Free PMC article.
278 results