Bucala R - Search Results

1

Crystallographic and receptor binding characterization of Plasmodium falciparum macrophage migration inhibitory factor complexed to two potent inhibitors.

Pantouris G, Rajasekaran D, Baeza Garcia A, Ruiz VG, Leng L, Jorgensen WL, Bucala R, Lolis EJ. Pantouris G, et al. Among authors: bucala r. J Med Chem. 2014 Oct 23;57(20):8652-6. doi: 10.1021/jm501168q. Epub 2014 Oct 8. J Med Chem. 2014. PMID: 25268646 Free PMC article.

2

Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor.

Sun HW, Bernhagen J, Bucala R, Lolis E. Sun HW, et al. Among authors: bucala r. Proc Natl Acad Sci U S A. 1996 May 28;93(11):5191-6. doi: 10.1073/pnas.93.11.5191. Proc Natl Acad Sci U S A. 1996. PMID: 8643551 Free PMC article.

3

The subunit structure of human macrophage migration inhibitory factor: evidence for a trimer.

Sun HW, Swope M, Cinquina C, Bedarkar S, Bernhagen J, Bucala R, Lolis E. Sun HW, et al. Among authors: bucala r. Protein Eng. 1996 Aug;9(8):631-5. doi: 10.1093/protein/9.8.631. Protein Eng. 1996. PMID: 8875640

4

Crystal structure of macrophage migration inhibitory factor (MIF), a glucocorticoid-induced regulator of cytokine production, reveals a unique architecture.

Lolis E, Bucala R. Lolis E, et al. Among authors: bucala r. Proc Assoc Am Physicians. 1996 Nov;108(6):415-9. Proc Assoc Am Physicians. 1996. PMID: 8956364 Review.

5

Inhibition of macrophage migration inhibitory factor (MIF) tautomerase activity by dopachrome analogs.

Zhang X, Bucala R. Zhang X, et al. Among authors: bucala r. Bioorg Med Chem Lett. 1999 Nov 15;9(22):3193-8. doi: 10.1016/s0960-894x(99)00561-2. Bioorg Med Chem Lett. 1999. PMID: 10576686

6

Inhibition of MIF bioactivity by rational design of pharmacological inhibitors of MIF tautomerase activity.

Dios A, Mitchell RA, Aljabari B, Lubetsky J, O'Connor K, Liao H, Senter PD, Manogue KR, Lolis E, Metz C, Bucala R, Callaway DJ, Al-Abed Y. Dios A, et al. Among authors: bucala r. J Med Chem. 2002 Jun 6;45(12):2410-6. doi: 10.1021/jm010534q. J Med Chem. 2002. PMID: 12036350

7

Macrophage migration inhibitory factor.

Lolis E, Bucala R. Lolis E, et al. Among authors: bucala r. Expert Opin Ther Targets. 2003 Apr;7(2):153-64. doi: 10.1517/14728222.7.2.153. Expert Opin Ther Targets. 2003. PMID: 12667094 Review.

8

MIF signal transduction initiated by binding to CD74.

Leng L, Metz CN, Fang Y, Xu J, Donnelly S, Baugh J, Delohery T, Chen Y, Mitchell RA, Bucala R. Leng L, et al. Among authors: bucala r. J Exp Med. 2003 Jun 2;197(11):1467-76. doi: 10.1084/jem.20030286. J Exp Med. 2003. PMID: 12782713 Free PMC article.

9

Therapeutic approaches to innate immunity: severe sepsis and septic shock.

Lolis E, Bucala R. Lolis E, et al. Among authors: bucala r. Nat Rev Drug Discov. 2003 Aug;2(8):635-45. doi: 10.1038/nrd1153. Nat Rev Drug Discov. 2003. PMID: 12904813 Review. No abstract available.

10

Evidence for a role of macrophage migration inhibitory factor in vascular disease.

Chen Z, Sakuma M, Zago AC, Zhang X, Shi C, Leng L, Mizue Y, Bucala R, Simon D. Chen Z, et al. Among authors: bucala r. Arterioscler Thromb Vasc Biol. 2004 Apr;24(4):709-14. doi: 10.1161/01.ATV.0000119356.35748.9e. Epub 2004 Jan 29. Arterioscler Thromb Vasc Biol. 2004. PMID: 14751814

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