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Programmable RNA recognition and cleavage by CRISPR/Cas9.
O'Connell MR, Oakes BL, Sternberg SH, East-Seletsky A, Kaplan M, Doudna JA. O'Connell MR, et al. Among authors: kaplan m. Nature. 2014 Dec 11;516(7530):263-6. doi: 10.1038/nature13769. Epub 2014 Sep 28. Nature. 2014. PMID: 25274302 Free PMC article.
Conformational control of DNA target cleavage by CRISPR-Cas9.
Sternberg SH, LaFrance B, Kaplan M, Doudna JA. Sternberg SH, et al. Among authors: kaplan m. Nature. 2015 Nov 5;527(7576):110-3. doi: 10.1038/nature15544. Epub 2015 Oct 28. Nature. 2015. PMID: 26524520 Free PMC article.
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA. Jinek M, et al. Among authors: kaplan m. Science. 2014 Mar 14;343(6176):1247997. doi: 10.1126/science.1247997. Epub 2014 Feb 6. Science. 2014. PMID: 24505130 Free PMC article.
MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi.
Raghunandanan S, Zhang K, Zhang Y, Priya R, Sze CW, Lou Y, Lynch MJ, Crane BR, Kaplan MH, Li C, Yang XF. Raghunandanan S, et al. Among authors: kaplan mh. PLoS Pathog. 2024 Dec 30;20(12):e1012327. doi: 10.1371/journal.ppat.1012327. eCollection 2024 Dec. PLoS Pathog. 2024. PMID: 39775665 Free PMC article.
Metabolic Targeting for Control of IL-9.
Lajiness JD, Kaplan MH. Lajiness JD, et al. Among authors: kaplan mh. J Invest Dermatol. 2025 Jan 8:S0022-202X(24)03019-7. doi: 10.1016/j.jid.2024.12.003. Online ahead of print. J Invest Dermatol. 2025. PMID: 39772348 No abstract available.
Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells.
Melo Garcia L, Gangadharan A, Banerjee P, Li Y, Zeng AGX, Rafei H, Lin P, Kumar B, Acharya S, Daher M, Muniz-Feliciano L, Deyter GM, Dominguez G, Park JM, Reyes Silva F, Nunez Cortes AK, Basar R, Uprety N, Shanley M, Kaplan M, Liu E, Shpall EJ, Rezvani K. Melo Garcia L, et al. Among authors: kaplan m. Cell Rep. 2025 Jan 3;44(1):115122. doi: 10.1016/j.celrep.2024.115122. Online ahead of print. Cell Rep. 2025. PMID: 39754720 Free article.
3,775 results