Nagaoka K - Search Results

1

Activation of intestinal human pregnane X receptor protects against azoxymethane/dextran sulfate sodium-induced colon cancer.

Cheng J, Fang ZZ, Nagaoka K, Okamoto M, Qu A, Tanaka N, Kimura S, Gonzalez FJ. Cheng J, et al. Among authors: nagaoka k. J Pharmacol Exp Ther. 2014 Dec;351(3):559-67. doi: 10.1124/jpet.114.215913. Epub 2014 Oct 2. J Pharmacol Exp Ther. 2014. PMID: 25277138 Free PMC article.

2

In vivo effects of the pure aryl hydrocarbon receptor antagonist GNF-351 after oral administration are limited to the gastrointestinal tract.

Fang ZZ, Krausz KW, Nagaoka K, Tanaka N, Gowda K, Amin SG, Perdew GH, Gonzalez FJ. Fang ZZ, et al. Among authors: nagaoka k. Br J Pharmacol. 2014 Apr;171(7):1735-46. doi: 10.1111/bph.12576. Br J Pharmacol. 2014. PMID: 24417285 Free PMC article.

3

Hypoxia-inducible factor/MAZ-dependent induction of caveolin-1 regulates colon permeability through suppression of occludin, leading to hypoxia-induced inflammation.

Xie L, Xue X, Taylor M, Ramakrishnan SK, Nagaoka K, Hao C, Gonzalez FJ, Shah YM. Xie L, et al. Among authors: nagaoka k. Mol Cell Biol. 2014 Aug;34(16):3013-23. doi: 10.1128/MCB.00324-14. Epub 2014 Jun 2. Mol Cell Biol. 2014. PMID: 24891620 Free PMC article.

4

Stereoselective glucuronidation of propranolol in human and cynomolgus monkey liver microsomes: role of human hepatic UDP-glucuronosyltransferase isoforms, UGT1A9, UGT2B4 and UGT2B7.

Hanioka N, Hayashi K, Shimizudani T, Nagaoka K, Koeda A, Naito S, Narimatsu S. Hanioka N, et al. Among authors: nagaoka k. Pharmacology. 2008;82(4):293-303. doi: 10.1159/000165100. Epub 2008 Oct 21. Pharmacology. 2008. PMID: 18936551

5

Comparative study of the oxidation of propranolol enantiomers in hepatic and small intestinal microsomes from cynomolgus and marmoset monkeys.

Shimizudani T, Nagaoka K, Hanioka N, Yamano S, Narimatsu S. Shimizudani T, et al. Among authors: nagaoka k. Chem Biol Interact. 2010 Jan 5;183(1):67-78. doi: 10.1016/j.cbi.2009.10.007. Chem Biol Interact. 2010. PMID: 19853591

6

Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes.

Hanioka N, Tanabe N, Jinno H, Tanaka-Kagawa T, Nagaoka K, Naito S, Koeda A, Narimatsu S. Hanioka N, et al. Among authors: nagaoka k. Life Sci. 2010 Aug 14;87(7-8):261-8. doi: 10.1016/j.lfs.2010.07.001. Epub 2010 Jul 8. Life Sci. 2010. PMID: 20620155

7

Regio- and stereoselective oxidation of propranolol enantiomers by human CYP2D6, cynomolgus monkey CYP2D17 and marmoset CYP2D19.

Narimatsu S, Nakata T, Shimizudani T, Nagaoka K, Nakura H, Masuda K, Katsu T, Koeda A, Naito S, Yamano S, Miyata A, Hanioka N. Narimatsu S, et al. Among authors: nagaoka k. Chem Biol Interact. 2011 Feb 1;189(3):146-52. doi: 10.1016/j.cbi.2010.12.014. Epub 2010 Dec 22. Chem Biol Interact. 2011. PMID: 21184751

8

Effect of UDP-glucuronosyltransferase 2B15 polymorphism on bisphenol A glucuronidation.

Hanioka N, Oka H, Nagaoka K, Ikushiro S, Narimatsu S. Hanioka N, et al. Among authors: nagaoka k. Arch Toxicol. 2011 Nov;85(11):1373-81. doi: 10.1007/s00204-011-0690-5. Epub 2011 Mar 15. Arch Toxicol. 2011. PMID: 21404072

9

Functional characterization of cynomolgus monkey UDP-glucuronosyltransferase 1A9.

Yamamoto K, Mukai M, Nagaoka K, Hayashi K, Hichiya H, Okada K, Murata M, Shigeyama M, Narimatsu S, Hanioka N. Yamamoto K, et al. Among authors: nagaoka k. Eur J Drug Metab Pharmacokinet. 2014 Sep;39(3):195-202. doi: 10.1007/s13318-014-0177-x. Epub 2014 Jan 28. Eur J Drug Metab Pharmacokinet. 2014. PMID: 24470170

10

The effects of N-glycosylation on the glucuronidation of zidovudine and morphine by UGT2B7 expressed in HEK293 cells.

Nagaoka K, Hanioka N, Ikushiro S, Yamano S, Narimatsu S. Nagaoka K, et al. Drug Metab Pharmacokinet. 2012;27(4):388-97. doi: 10.2133/dmpk.dmpk-11-rg-135. Epub 2012 Jan 13. Drug Metab Pharmacokinet. 2012. PMID: 22240840 Free article.

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