Chen P - Search Results

1

UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers.

Wassenaar CA, Conti DV, Das S, Chen P, Cook EH, Ratain MJ, Benowitz NL, Tyndale RF. Wassenaar CA, et al. Among authors: chen p. Cancer Epidemiol Biomarkers Prev. 2015 Jan;24(1):94-104. doi: 10.1158/1055-9965.EPI-14-0804. Epub 2014 Oct 2. Cancer Epidemiol Biomarkers Prev. 2015. PMID: 25277794 Free PMC article.

2

Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism.

Liu W, Innocenti F, Chen P, Das S, Cook EH Jr, Ratain MJ. Liu W, et al. Among authors: chen p. Clin Cancer Res. 2003 Mar;9(3):1009-12. Clin Cancer Res. 2003. PMID: 12631599

3

Haplotypes of variants in the UDP-glucuronosyltransferase1A9 and 1A1 genes.

Innocenti F, Liu W, Chen P, Desai AA, Das S, Ratain MJ. Innocenti F, et al. Among authors: chen p. Pharmacogenet Genomics. 2005 May;15(5):295-301. doi: 10.1097/01213011-200505000-00004. Pharmacogenet Genomics. 2005. PMID: 15864130

4

Genetic factors affecting gene transcription and catalytic activity of UDP-glucuronosyltransferases in human liver.

Liu W, Ramírez J, Gamazon ER, Mirkov S, Chen P, Wu K, Sun C, Cox NJ, Cook E Jr, Das S, Ratain MJ. Liu W, et al. Among authors: chen p. Hum Mol Genet. 2014 Oct 15;23(20):5558-69. doi: 10.1093/hmg/ddu268. Epub 2014 May 30. Hum Mol Genet. 2014. PMID: 24879639 Free PMC article.

5

Hepatocyte nuclear factor-1 alpha is associated with UGT1A1, UGT1A9 and UGT2B7 mRNA expression in human liver.

Ramírez J, Mirkov S, Zhang W, Chen P, Das S, Liu W, Ratain MJ, Innocenti F. Ramírez J, et al. Among authors: chen p. Pharmacogenomics J. 2008 Apr;8(2):152-61. doi: 10.1038/sj.tpj.6500454. Epub 2007 Apr 17. Pharmacogenomics J. 2008. PMID: 17440429

6

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan.

Innocenti F, Undevia SD, Iyer L, Chen PX, Das S, Kocherginsky M, Karrison T, Janisch L, Ramírez J, Rudin CM, Vokes EE, Ratain MJ. Innocenti F, et al. J Clin Oncol. 2004 Apr 15;22(8):1382-8. doi: 10.1200/JCO.2004.07.173. Epub 2004 Mar 8. J Clin Oncol. 2004. PMID: 15007088

7

Lack of association between common polymorphisms in UGT1A9 and gene expression and activity.

Ramírez J, Liu W, Mirkov S, Desai AA, Chen P, Das S, Innocenti F, Ratain MJ. Ramírez J, et al. Among authors: chen p. Drug Metab Dispos. 2007 Dec;35(12):2149-53. doi: 10.1124/dmd.107.015446. Epub 2007 Aug 30. Drug Metab Dispos. 2007. PMID: 17761781

8

Determination and analysis of single nucleotide polymorphisms and haplotype structure of the human carboxylesterase 2 gene.

Wu MH, Chen P, Wu X, Liu W, Strom S, Das S, Cook EH Jr, Rosner GL, Dolan ME. Wu MH, et al. Among authors: chen p. Pharmacogenetics. 2004 Sep;14(9):595-605. doi: 10.1097/00008571-200409000-00004. Pharmacogenetics. 2004. PMID: 15475733

9

Population-specific GSTM1 copy number variation.

Huang RS, Chen P, Wisel S, Duan S, Zhang W, Cook EH, Das S, Cox NJ, Dolan ME. Huang RS, et al. Among authors: chen p. Hum Mol Genet. 2009 Jan 15;18(2):366-72. doi: 10.1093/hmg/ddn345. Epub 2008 Oct 23. Hum Mol Genet. 2009. PMID: 18948376 Free PMC article.

10

Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: the example of the novel anticancer agent ABT-751.

Innocenti F, Ramírez J, Obel J, Xiong J, Mirkov S, Chiu YL, Katz DA, Carr RA, Zhang W, Das S, Adjei A, Moyer AM, Chen PX, Krivoshik A, Medina D, Gordon GB, Ratain MJ, Sahelijo L, Weinshilboum RM, Fleming GF, Bhathena A. Innocenti F, et al. Pharmacogenet Genomics. 2013 Jul;23(7):374-81. doi: 10.1097/FPC.0b013e3283623e81. Pharmacogenet Genomics. 2013. PMID: 23670235 Free PMC article. Clinical Trial.

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