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High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling.
Medyouf H, Gusscott S, Wang H, Tseng JC, Wai C, Nemirovsky O, Trumpp A, Pflumio F, Carboni J, Gottardis M, Pollak M, Kung AL, Aster JC, Holzenberger M, Weng AP. Medyouf H, et al. Among authors: weng ap. J Exp Med. 2011 Aug 29;208(9):1809-22. doi: 10.1084/jem.20110121. Epub 2011 Aug 1. J Exp Med. 2011. PMID: 21807868 Free PMC article.
Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma.
Kridel R, Meissner B, Rogic S, Boyle M, Telenius A, Woolcock B, Gunawardana J, Jenkins CE, Cochrane C, Ben-Neriah S, Tan K, Morin RD, Opat S, Sehn LH, Connors JM, Marra MA, Weng AP, Steidl C, Gascoyne RD. Kridel R, et al. Among authors: weng ap. Blood. 2012 Mar 1;119(9):1963-71. doi: 10.1182/blood-2011-11-391474. Epub 2011 Dec 30. Blood. 2012. PMID: 22210878 Free article.
CD44 promotes chemoresistance in T-ALL by increased drug efflux.
Hoofd C, Wang X, Lam S, Jenkins C, Wood B, Giambra V, Weng AP. Hoofd C, et al. Among authors: weng ap. Exp Hematol. 2016 Mar;44(3):166-71.e17. doi: 10.1016/j.exphem.2015.12.001. Epub 2015 Dec 18. Exp Hematol. 2016. PMID: 26708679 Free article.
Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD.
Yuan T, Yang Y, Chen J, Li W, Li W, Zhang Q, Mi Y, Goswami RS, You JQ, Lin D, Qian MD, Calin S, Liang Y, Miranda RN, Calin GA, Zhou X, Ma L, Zweidler-McKay PA, Liu B, Weng AP, Medeiros LJ, Zhang Y, You MJ. Yuan T, et al. Among authors: weng ap. Leukemia. 2017 Nov;31(11):2355-2364. doi: 10.1038/leu.2017.80. Epub 2017 Mar 10. Leukemia. 2017. PMID: 28280276 Free PMC article.
93 results