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Mapping chromatin interactions at melanoma susceptibility loci and cell-type specific dataset integration uncovers distant gene targets of cis -regulation.
Thakur R, Xu M, Sowards H, Yon J, Jessop L, Myers T, Zhang T, Chari R, Long E, Rehling T, Hennessey R, Funderburk K, Yin J, Machiela MJ, Johnson ME, Wells AD, Chesi A, Grant SFA, Iles MM, Landi MT, Law MH; Melanoma Meta-Analysis Consortium; Choi J, Brown KM. Thakur R, et al. Among authors: grant sfa. medRxiv [Preprint]. 2024 Nov 15:2024.11.14.24317204. doi: 10.1101/2024.11.14.24317204. medRxiv. 2024. PMID: 39802764 Free PMC article. Preprint.
A framework for conducting GWAS using repeated measures data with an application to childhood BMI.
Burrows K, Heiskala A, Bradfield JP, Balkhiyarova Z, Ning L, Boissel M, Chan YM, Froguel P, Bonnefond A, Hakonarson H, Alves AC, Lawlor DA, Kaakinen M, Järvelin MR, Grant SFA, Tilling K, Prokopenko I, Sebert S, Canouil M, Warrington NM. Burrows K, et al. Among authors: grant sfa. Nat Commun. 2024 Nov 20;15(1):10067. doi: 10.1038/s41467-024-53687-3. Nat Commun. 2024. PMID: 39567492 Free PMC article.
Large-scale multi-omic analysis identifies noncoding somatic driver mutations and nominates ZFP36L2 as a driver gene for pancreatic ductal adenocarcinoma.
Zhong J, O'Brien A, Patel M, Eiser D, Mobaraki M, Collins I, Wang L, Guo K, TruongVo T, Jermusyk A, O'Neill M, Dill CD, Wells AD, Leonard ME, Pippin JA, Grant SFA, Zhang T, Andresson T, Connelly KE, Shi J, Arda HE, Hoskins JW, Amundadottir LT. Zhong J, et al. Among authors: grant sfa. medRxiv [Preprint]. 2024 Sep 24:2024.09.22.24314165. doi: 10.1101/2024.09.22.24314165. medRxiv. 2024. PMID: 39371173 Free PMC article. Preprint.
348 results