Hammer RE - Search Results

1

Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance.

Moon YA, Ochoa CR, Mitsche MA, Hammer RE, Horton JD. Moon YA, et al. Among authors: hammer re. J Lipid Res. 2014 Dec;55(12):2597-605. doi: 10.1194/jlr.M054353. Epub 2014 Oct 3. J Lipid Res. 2014. PMID: 25281760 Free PMC article.

2

Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice.

Moon YA, Hammer RE, Horton JD. Moon YA, et al. Among authors: hammer re. J Lipid Res. 2009 Mar;50(3):412-423. doi: 10.1194/jlr.M800383-JLR200. Epub 2008 Oct 6. J Lipid Res. 2009. PMID: 18838740 Free PMC article.

3

Overexpression of sterol regulatory element-binding protein-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver.

Horton JD, Shimomura I, Ikemoto S, Bashmakov Y, Hammer RE. Horton JD, et al. Among authors: hammer re. J Biol Chem. 2003 Sep 19;278(38):36652-60. doi: 10.1074/jbc.M306540200. Epub 2003 Jul 10. J Biol Chem. 2003. PMID: 12855691 Free article.

4

Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis.

Engelking LJ, Kuriyama H, Hammer RE, Horton JD, Brown MS, Goldstein JL, Liang G. Engelking LJ, et al. Among authors: hammer re. J Clin Invest. 2004 Apr;113(8):1168-75. doi: 10.1172/JCI20978. J Clin Invest. 2004. PMID: 15085196 Free PMC article.

5

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9.

Rashid S, Curtis DE, Garuti R, Anderson NN, Bashmakov Y, Ho YK, Hammer RE, Moon YA, Horton JD. Rashid S, et al. Among authors: hammer re. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5374-9. doi: 10.1073/pnas.0501652102. Epub 2005 Apr 1. Proc Natl Acad Sci U S A. 2005. PMID: 15805190 Free PMC article.

6

Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy.

Cortés VA, Curtis DE, Sukumaran S, Shao X, Parameswara V, Rashid S, Smith AR, Ren J, Esser V, Hammer RE, Agarwal AK, Horton JD, Garg A. Cortés VA, et al. Among authors: hammer re. Cell Metab. 2009 Feb;9(2):165-76. doi: 10.1016/j.cmet.2009.01.002. Cell Metab. 2009. PMID: 19187773 Free PMC article.

7

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice.

Rong S, Cortés VA, Rashid S, Anderson NN, McDonald JG, Liang G, Moon YA, Hammer RE, Horton JD. Rong S, et al. Among authors: hammer re. Elife. 2017 Feb 28;6:e25015. doi: 10.7554/eLife.25015. Elife. 2017. PMID: 28244871 Free PMC article.

8

Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice.

Linden AG, Li S, Choi HY, Fang F, Fukasawa M, Uyeda K, Hammer RE, Horton JD, Engelking LJ, Liang G. Linden AG, et al. Among authors: hammer re. J Lipid Res. 2018 Mar;59(3):475-487. doi: 10.1194/jlr.M081836. Epub 2018 Jan 15. J Lipid Res. 2018. PMID: 29335275 Free PMC article.

9

SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation.

Matsuda M, Korn BS, Hammer RE, Moon YA, Komuro R, Horton JD, Goldstein JL, Brown MS, Shimomura I. Matsuda M, et al. Among authors: hammer re. Genes Dev. 2001 May 15;15(10):1206-16. doi: 10.1101/gad.891301. Genes Dev. 2001. PMID: 11358865 Free PMC article.

10

Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene.

Yang J, Goldstein JL, Hammer RE, Moon YA, Brown MS, Horton JD. Yang J, et al. Among authors: hammer re. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13607-12. doi: 10.1073/pnas.201524598. Proc Natl Acad Sci U S A. 2001. PMID: 11717426 Free PMC article.

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