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Codelivery of antigen and an immune cell adhesion inhibitor is necessary for efficacy of soluble antigen arrays in experimental autoimmune encephalomyelitis.
Sestak JO, Sullivan BP, Thati S, Northrup L, Hartwell B, Antunez L, Forrest ML, Vines CM, Siahaan TJ, Berkland C. Sestak JO, et al. Among authors: thati s. Mol Ther Methods Clin Dev. 2014 Apr 9;1:14008. doi: 10.1038/mtm.2014.8. eCollection 2014. Mol Ther Methods Clin Dev. 2014. PMID: 26015953 Free PMC article.
Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation.
Song JY, Larson NR, Thati S, Torres-Vazquez I, Martinez-Rivera N, Subelzu NJ, Leon MA, Rosa-Molinar E, Schöneich C, Forrest ML, Middaugh CR, Berkland CJ. Song JY, et al. Among authors: thati s. J Control Release. 2019 Jan 10;293:36-47. doi: 10.1016/j.jconrel.2018.11.007. Epub 2018 Nov 7. J Control Release. 2019. PMID: 30414463 Free PMC article.
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