Garcia KC - Search Results

1

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies.

Goehring A, Lee CH, Wang KH, Michel JC, Claxton DP, Baconguis I, Althoff T, Fischer S, Garcia KC, Gouaux E. Goehring A, et al. Among authors: garcia kc. Nat Protoc. 2014 Nov;9(11):2574-85. doi: 10.1038/nprot.2014.173. Epub 2014 Oct 9. Nat Protoc. 2014. PMID: 25299155 Free PMC article.

2

Structure of the Nogo receptor ectodomain: a recognition module implicated in myelin inhibition.

He XL, Bazan JF, McDermott G, Park JB, Wang K, Tessier-Lavigne M, He Z, Garcia KC. He XL, et al. Among authors: garcia kc. Neuron. 2003 Apr 24;38(2):177-85. doi: 10.1016/s0896-6273(03)00232-0. Neuron. 2003. PMID: 12718853 Free article.

3

BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies.

Dukkipati A, Park HH, Waghray D, Fischer S, Garcia KC. Dukkipati A, et al. Among authors: garcia kc. Protein Expr Purif. 2008 Dec;62(2):160-70. doi: 10.1016/j.pep.2008.08.004. Epub 2008 Aug 22. Protein Expr Purif. 2008. PMID: 18782620 Free PMC article.

4

Structural basis of receptor sharing by interleukin 17 cytokines.

Ely LK, Fischer S, Garcia KC. Ely LK, et al. Among authors: garcia kc. Nat Immunol. 2009 Dec;10(12):1245-51. doi: 10.1038/ni.1813. Epub 2009 Oct 18. Nat Immunol. 2009. PMID: 19838198 Free PMC article.

5

Structural snapshots of full-length Jak1, a transmembrane gp130/IL-6/IL-6Rα cytokine receptor complex, and the receptor-Jak1 holocomplex.

Lupardus PJ, Skiniotis G, Rice AJ, Thomas C, Fischer S, Walz T, Garcia KC. Lupardus PJ, et al. Among authors: garcia kc. Structure. 2011 Jan 12;19(1):45-55. doi: 10.1016/j.str.2010.10.010. Structure. 2011. PMID: 21220115 Free PMC article.

6

Molecular architecture of the αβ T cell receptor-CD3 complex.

Birnbaum ME, Berry R, Hsiao YS, Chen Z, Shingu-Vazquez MA, Yu X, Waghray D, Fischer S, McCluskey J, Rossjohn J, Walz T, Garcia KC. Birnbaum ME, et al. Among authors: garcia kc. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17576-81. doi: 10.1073/pnas.1420936111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422432 Free PMC article.

7

Structural biology. Structural basis for Notch1 engagement of Delta-like 4.

Luca VC, Jude KM, Pierce NW, Nachury MV, Fischer S, Garcia KC. Luca VC, et al. Among authors: garcia kc. Science. 2015 Feb 20;347(6224):847-53. doi: 10.1126/science.1261093. Science. 2015. PMID: 25700513 Free PMC article.

8

Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.

Mitra S, Ring AM, Amarnath S, Spangler JB, Li P, Ju W, Fischer S, Oh J, Spolski R, Weiskopf K, Kohrt H, Foley JE, Rajagopalan S, Long EO, Fowler DH, Waldmann TA, Garcia KC, Leonard WJ. Mitra S, et al. Among authors: garcia kc. Immunity. 2015 May 19;42(5):826-38. doi: 10.1016/j.immuni.2015.04.018. Immunity. 2015. PMID: 25992859 Free PMC article.

9

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.

Gee MH, Han A, Lofgren SM, Beausang JF, Mendoza JL, Birnbaum ME, Bethune MT, Fischer S, Yang X, Gomez-Eerland R, Bingham DB, Sibener LV, Fernandes RA, Velasco A, Baltimore D, Schumacher TN, Khatri P, Quake SR, Davis MM, Garcia KC. Gee MH, et al. Among authors: garcia kc. Cell. 2018 Jan 25;172(3):549-563.e16. doi: 10.1016/j.cell.2017.11.043. Epub 2017 Dec 21. Cell. 2018. PMID: 29275860 Free PMC article.

10

Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity.

Mendoza JL, Fischer S, Gee MH, Lam LH, Brackenridge S, Powrie FM, Birnbaum M, McMichael AJ, Garcia KC, Gillespie GM. Mendoza JL, et al. Among authors: garcia kc. Elife. 2020 Jul 27;9:e58128. doi: 10.7554/eLife.58128. Elife. 2020. PMID: 32716298 Free PMC article.

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