Almeida AM - Search Results

1

A γ-amino acid that favors 12/10-helical secondary structure in α/γ-peptides.

Giuliano MW, Maynard SJ, Almeida AM, Guo L, Guzei IA, Spencer LC, Gellman SH. Giuliano MW, et al. Among authors: almeida am. J Am Chem Soc. 2014 Oct 22;136(42):15046-53. doi: 10.1021/ja5076585. Epub 2014 Oct 10. J Am Chem Soc. 2014. PMID: 25301259

2

Stereospecific synthesis of conformationally constrained gamma-amino acids: new foldamer building blocks that support helical secondary structure.

Guo L, Chi Y, Almeida AM, Guzei IA, Parker BK, Gellman SH. Guo L, et al. Among authors: almeida am. J Am Chem Soc. 2009 Nov 11;131(44):16018-20. doi: 10.1021/ja907233q. J Am Chem Soc. 2009. PMID: 19886693 Free PMC article.

3

Helix formation in preorganized beta/gamma-peptide foldamers: hydrogen-bond analogy to the alpha-helix without alpha-amino acid residues.

Guo L, Almeida AM, Zhang W, Reidenbach AG, Choi SH, Guzei IA, Gellman SH. Guo L, et al. Among authors: almeida am. J Am Chem Soc. 2010 Jun 16;132(23):7868-9. doi: 10.1021/ja103233a. J Am Chem Soc. 2010. PMID: 20491510 Free PMC article.

4

Parallel β-sheet secondary structure is stabilized and terminated by interstrand disulfide cross-linking.

Almeida AM, Li R, Gellman SH. Almeida AM, et al. J Am Chem Soc. 2012 Jan 11;134(1):75-8. doi: 10.1021/ja208856c. Epub 2011 Dec 13. J Am Chem Soc. 2012. PMID: 22148521 Free PMC article.

5

Parallel β-sheet vibrational couplings revealed by 2D IR spectroscopy of an isotopically labeled macrocycle: quantitative benchmark for the interpretation of amyloid and protein infrared spectra.

Woys AM, Almeida AM, Wang L, Chiu CC, McGovern M, de Pablo JJ, Skinner JL, Gellman SH, Zanni MT. Woys AM, et al. Among authors: almeida am. J Am Chem Soc. 2012 Nov 21;134(46):19118-28. doi: 10.1021/ja3074962. Epub 2012 Nov 9. J Am Chem Soc. 2012. PMID: 23113791 Free PMC article.

6

Evaluation of a cyclopentane-based γ-amino acid for the ability to promote α/γ-peptide secondary structure.

Giuliano MW, Maynard SJ, Almeida AM, Reidenbach AG, Guo L, Ulrich EC, Guzei IA, Gellman SH. Giuliano MW, et al. Among authors: almeida am. J Org Chem. 2013 Dec 20;78(24):12351-61. doi: 10.1021/jo401501g. Epub 2013 Dec 5. J Org Chem. 2013. PMID: 24303945 Free PMC article.

7

New charge-bearing amino acid residues that promote β-sheet secondary structure.

Maynard SJ, Almeida AM, Yoshimi Y, Gellman SH. Maynard SJ, et al. Among authors: almeida am. J Am Chem Soc. 2014 Nov 26;136(47):16683-8. doi: 10.1021/ja510265e. Epub 2014 Nov 13. J Am Chem Soc. 2014. PMID: 25393077 Free PMC article.

8

Impact of strand length on the stability of parallel-β-sheet secondary structure.

Freire F, Almeida AM, Fisk JD, Steinkruger JD, Gellman SH. Freire F, et al. Among authors: almeida am. Angew Chem Int Ed Engl. 2011 Sep 5;50(37):8735-8. doi: 10.1002/anie.201102986. Epub 2011 Aug 2. Angew Chem Int Ed Engl. 2011. PMID: 21812082 Free PMC article. No abstract available.

9

Chromatographic capture of cells to achieve single stage clarification in recombinant protein purification.

Almeida A, Chau D, Coolidge T, El-Sabbahy H, Hager S, Jose K, Nakamura M, Voloshin A. Almeida A, et al. Biotechnol Prog. 2022 Mar;38(2):e3227. doi: 10.1002/btpr.3227. Epub 2021 Dec 8. Biotechnol Prog. 2022. PMID: 34854259 Free PMC article.

10

HIF2α-Targeted RNAi Therapeutic Inhibits Clear Cell Renal Cell Carcinoma.

Wong SC, Cheng W, Hamilton H, Nicholas AL, Wakefield DH, Almeida A, Blokhin AV, Carlson J, Neal ZC, Subbotin V, Zhang G, Hegge J, Bertin S, Trubetskoy VS, Rozema DB, Lewis DL, Kanner SB. Wong SC, et al. Mol Cancer Ther. 2018 Jan;17(1):140-149. doi: 10.1158/1535-7163.MCT-17-0471. Epub 2017 Oct 27. Mol Cancer Ther. 2018. PMID: 29079709

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