Lesinski GB - Search Results

1

Patients with pancreatic adenocarcinoma exhibit elevated levels of myeloid-derived suppressor cells upon progression of disease.

Markowitz J, Brooks TR, Duggan MC, Paul BK, Pan X, Wei L, Abrams Z, Luedke E, Lesinski GB, Mundy-Bosse B, Bekaii-Saab T, Carson WE 3rd. Markowitz J, et al. Among authors: lesinski gb. Cancer Immunol Immunother. 2015 Feb;64(2):149-59. doi: 10.1007/s00262-014-1618-8. Epub 2014 Oct 11. Cancer Immunol Immunother. 2015. PMID: 25305035 Free PMC article.

2

The degree of T cell stemness differentially impacts the potency of adoptive cancer immunotherapy in a Lef-1 and Tcf-1 dependent manner.

Rangel Rivera GO, Dwyer CJ, Knochelmann HM, Smith AS, Aksoy A, Cole AC, Wyatt MM, Thaxton JE, Lesinski GB, Paulos CM. Rangel Rivera GO, et al. Among authors: lesinski gb. bioRxiv [Preprint]. 2023 Mar 10:2023.03.08.531589. doi: 10.1101/2023.03.08.531589. bioRxiv. 2023. PMID: 36945574 Free PMC article. Preprint.

3

Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity.

Rangel Rivera GO, Dwyer CJ, Knochelmann HM, Smith AS, Aksoy BA, Cole AC, Wyatt MM, Kumaresan S, Thaxton JE, Lesinski GB, Paulos CM. Rangel Rivera GO, et al. Among authors: lesinski gb. Cancer Res. 2024 Jan 2;84(1):69-83. doi: 10.1158/0008-5472.CAN-23-0801. Cancer Res. 2024. PMID: 37801615

4

The antitumor effects of IFN-alpha are abrogated in a STAT1-deficient mouse.

Lesinski GB, Anghelina M, Zimmerer J, Bakalakos T, Badgwell B, Parihar R, Hu Y, Becknell B, Abood G, Chaudhury AR, Magro C, Durbin J, Carson WE 3rd. Lesinski GB, et al. J Clin Invest. 2003 Jul;112(2):170-80. doi: 10.1172/JCI16603. J Clin Invest. 2003. PMID: 12865406 Free PMC article.

5

The antitumor effects of interferon-alpha are maintained in mice challenged with a STAT1-deficient murine melanoma cell line.

Badgwell B, Lesinski GB, Magro C, Abood G, Skaf A, Carson W 3rd. Badgwell B, et al. Among authors: lesinski gb. J Surg Res. 2004 Jan;116(1):129-36. doi: 10.1016/j.jss.2003.09.005. J Surg Res. 2004. PMID: 14732359

6

IL-12 pretreatments enhance IFN-alpha-induced Janus kinase-STAT signaling and potentiate the antitumor effects of IFN-alpha in a murine model of malignant melanoma.

Lesinski GB, Badgwell B, Zimmerer J, Crespin T, Hu Y, Abood G, Carson WE 3rd. Lesinski GB, et al. J Immunol. 2004 Jun 15;172(12):7368-76. doi: 10.4049/jimmunol.172.12.7368. J Immunol. 2004. PMID: 15187113

7

Multiparametric flow cytometric analysis of inter-patient variation in STAT1 phosphorylation following interferon Alfa immunotherapy.

Lesinski GB, Kondadasula SV, Crespin T, Shen L, Kendra K, Walker M, Carson WE 3rd. Lesinski GB, et al. J Natl Cancer Inst. 2004 Sep 1;96(17):1331-42. doi: 10.1093/jnci/djh252. J Natl Cancer Inst. 2004. PMID: 15339971

8

Expression of STAT1 and STAT2 in malignant melanoma does not correlate with response to interferon-alpha adjuvant therapy.

Lesinski GB, Valentino D, Hade EM, Jones S, Magro C, Chaudhury AR, Walker MJ, Carson WE 3rd. Lesinski GB, et al. Cancer Immunol Immunother. 2005 Sep;54(9):815-25. doi: 10.1007/s00262-004-0649-y. Epub 2005 Jan 25. Cancer Immunol Immunother. 2005. PMID: 15668815 Free PMC article.

9

Release of biologically functional interferon-alpha from a nanochannel delivery system.

Lesinski GB, Sharma S, Varker KA, Sinha P, Ferrari M, Carson WE 3rd. Lesinski GB, et al. Biomed Microdevices. 2005 Mar;7(1):71-9. doi: 10.1007/s10544-005-6174-8. Biomed Microdevices. 2005. PMID: 15834523

10

Phase I study of the sequential combination of interleukin-12 and interferon alfa-2b in advanced cancer: evidence for modulation of interferon signaling pathways by interleukin-12.

Eisenbeis CF, Lesinski GB, Anghelina M, Parihar R, Valentino D, Liu J, Nadella P, Sundaram P, Young DC, Sznol M, Walker MJ, Carson WE 3rd. Eisenbeis CF, et al. Among authors: lesinski gb. J Clin Oncol. 2005 Dec 1;23(34):8835-44. doi: 10.1200/JCO.2005.02.1691. J Clin Oncol. 2005. PMID: 16314644 Clinical Trial.

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