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428 results

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Page 1
Optical control of insulin release using a photoswitchable sulfonylurea.
Broichhagen J, Schönberger M, Cork SC, Frank JA, Marchetti P, Bugliani M, Shapiro AM, Trapp S, Rutter GA, Hodson DJ, Trauner D. Broichhagen J, et al. Among authors: rutter ga. Nat Commun. 2014 Oct 14;5:5116. doi: 10.1038/ncomms6116. Nat Commun. 2014. PMID: 25311795 Free PMC article.
A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults.
Tarasov AI, Nicolson TJ, Riveline JP, Taneja TK, Baldwin SA, Baldwin JM, Charpentier G, Gautier JF, Froguel P, Vaxillaire M, Rutter GA. Tarasov AI, et al. Among authors: rutter ga. Diabetes. 2008 Jun;57(6):1595-604. doi: 10.2337/db07-1547. Epub 2008 Mar 17. Diabetes. 2008. PMID: 18346985 Free PMC article.
Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells.
Dominguez V, Raimondi C, Somanath S, Bugliani M, Loder MK, Edling CE, Divecha N, da Silva-Xavier G, Marselli L, Persaud SJ, Turner MD, Rutter GA, Marchetti P, Falasca M, Maffucci T. Dominguez V, et al. Among authors: rutter ga. J Biol Chem. 2011 Feb 11;286(6):4216-25. doi: 10.1074/jbc.M110.200295. Epub 2010 Dec 2. J Biol Chem. 2011. PMID: 21127054 Free PMC article.
Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.
da Silva Xavier G, Farhan H, Kim H, Caxaria S, Johnson P, Hughes S, Bugliani M, Marselli L, Marchetti P, Birzele F, Sun G, Scharfmann R, Rutter J, Siniakowicz K, Weir G, Parker H, Reimann F, Gribble FM, Rutter GA. da Silva Xavier G, et al. Among authors: rutter ga, rutter j. Diabetologia. 2011 Apr;54(4):819-27. doi: 10.1007/s00125-010-2010-7. Epub 2010 Dec 23. Diabetologia. 2011. PMID: 21181396 Free PMC article.
Lipotoxicity disrupts incretin-regulated human β cell connectivity.
Hodson DJ, Mitchell RK, Bellomo EA, Sun G, Vinet L, Meda P, Li D, Li WH, Bugliani M, Marchetti P, Bosco D, Piemonti L, Johnson P, Hughes SJ, Rutter GA. Hodson DJ, et al. Among authors: rutter ga. J Clin Invest. 2013 Oct;123(10):4182-94. doi: 10.1172/JCI68459. Epub 2013 Sep 9. J Clin Invest. 2013. PMID: 24018562 Free PMC article.
ADCY5 couples glucose to insulin secretion in human islets.
Hodson DJ, Mitchell RK, Marselli L, Pullen TJ, Gimeno Brias S, Semplici F, Everett KL, Cooper DM, Bugliani M, Marchetti P, Lavallard V, Bosco D, Piemonti L, Johnson PR, Hughes SJ, Li D, Li WH, Shapiro AM, Rutter GA. Hodson DJ, et al. Among authors: rutter ga. Diabetes. 2014 Sep;63(9):3009-21. doi: 10.2337/db13-1607. Epub 2014 Apr 16. Diabetes. 2014. PMID: 24740569 Free PMC article.
Incretin-modulated beta cell energetics in intact islets of Langerhans.
Hodson DJ, Tarasov AI, Gimeno Brias S, Mitchell RK, Johnston NR, Haghollahi S, Cane MC, Bugliani M, Marchetti P, Bosco D, Johnson PR, Hughes SJ, Rutter GA. Hodson DJ, et al. Among authors: rutter ga. Mol Endocrinol. 2014 Jun;28(6):860-71. doi: 10.1210/me.2014-1038. Epub 2014 Apr 25. Mol Endocrinol. 2014. PMID: 24766140 Free PMC article.
428 results