de Juan-Sanz J - Search Results

1

Presynaptic control of glycine transporter 2 (GlyT2) by physical and functional association with plasma membrane Ca2+-ATPase (PMCA) and Na+-Ca2+ exchanger (NCX).

de Juan-Sanz J, Núñez E, Zafra F, Berrocal M, Corbacho I, Ibáñez I, Arribas-González E, Marcos D, López-Corcuera B, Mata AM, Aragón C. de Juan-Sanz J, et al. J Biol Chem. 2014 Dec 5;289(49):34308-24. doi: 10.1074/jbc.M114.586966. Epub 2014 Oct 14. J Biol Chem. 2014. PMID: 25315779 Free PMC article.

2

E3 ubiquitin ligases LNX1 and LNX2 are major regulators of the presynaptic glycine transporter GlyT2.

de la Rocha-Muñoz A, Núñez E, Arribas-González E, López-Corcuera B, Aragón C, de Juan-Sanz J. de la Rocha-Muñoz A, et al. Sci Rep. 2019 Oct 18;9(1):14944. doi: 10.1038/s41598-019-51301-x. Sci Rep. 2019. PMID: 31628376 Free PMC article.

3

Endocytosis of the neuronal glycine transporter GLYT2: role of membrane rafts and protein kinase C-dependent ubiquitination.

de Juan-Sanz J, Zafra F, López-Corcuera B, Aragón C. de Juan-Sanz J, et al. Traffic. 2011 Dec;12(12):1850-67. doi: 10.1111/j.1600-0854.2011.01278.x. Epub 2011 Oct 9. Traffic. 2011. PMID: 21910806 Free article.

4

A novel dominant hyperekplexia mutation Y705C alters trafficking and biochemical properties of the presynaptic glycine transporter GlyT2.

Giménez C, Pérez-Siles G, Martínez-Villarreal J, Arribas-González E, Jiménez E, Núñez E, de Juan-Sanz J, Fernández-Sánchez E, García-Tardón N, Ibáñez I, Romanelli V, Nevado J, James VM, Topf M, Chung SK, Thomas RH, Desviat LR, Aragón C, Zafra F, Rees MI, Lapunzina P, Harvey RJ, López-Corcuera B. Giménez C, et al. J Biol Chem. 2012 Aug 17;287(34):28986-9002. doi: 10.1074/jbc.M111.319244. Epub 2012 Jun 29. J Biol Chem. 2012. PMID: 22753417 Free PMC article. Clinical Trial.

5

Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster.

de Juan-Sanz J, Núñez E, López-Corcuera B, Aragón C. de Juan-Sanz J, et al. PLoS One. 2013;8(3):e58863. doi: 10.1371/journal.pone.0058863. Epub 2013 Mar 6. PLoS One. 2013. PMID: 23484054 Free PMC article.

6

Na+/K+-ATPase is a new interacting partner for the neuronal glycine transporter GlyT2 that downregulates its expression in vitro and in vivo.

de Juan-Sanz J, Núñez E, Villarejo-López L, Pérez-Hernández D, Rodriguez-Fraticelli AE, López-Corcuera B, Vázquez J, Aragón C. de Juan-Sanz J, et al. J Neurosci. 2013 Aug 28;33(35):14269-81. doi: 10.1523/JNEUROSCI.1532-13.2013. J Neurosci. 2013. PMID: 23986260 Free PMC article.

7

Molecular basis of the dominant negative effect of a glycine transporter 2 mutation associated with hyperekplexia.

Arribas-González E, de Juan-Sanz J, Aragón C, López-Corcuera B. Arribas-González E, et al. J Biol Chem. 2015 Jan 23;290(4):2150-65. doi: 10.1074/jbc.M114.587055. Epub 2014 Dec 5. J Biol Chem. 2015. PMID: 25480793 Free PMC article.

8

The presynaptic glycine transporter GlyT2 is regulated by the Hedgehog pathway in vitro and in vivo.

de la Rocha-Muñoz A, Núñez E, Vishwanath AA, Gómez-López S, Dhanasobhon D, Rebola N, López-Corcuera B, de Juan-Sanz J, Aragón C. de la Rocha-Muñoz A, et al. Among authors: de juan sanz j. Commun Biol. 2021 Oct 18;4(1):1197. doi: 10.1038/s42003-021-02718-6. Commun Biol. 2021. PMID: 34663888 Free PMC article.

9

Axonal Endoplasmic Reticulum Ca²⁺ Content Controls Release Probability in CNS Nerve Terminals.

de Juan-Sanz J, Holt GT, Schreiter ER, de Juan F, Kim DS, Ryan TA. de Juan-Sanz J, et al. Neuron. 2017 Feb 22;93(4):867-881.e6. doi: 10.1016/j.neuron.2017.01.010. Epub 2017 Feb 2. Neuron. 2017. PMID: 28162809 Free PMC article.

10

Molecular Tuning of the Axonal Mitochondrial Ca²⁺ Uniporter Ensures Metabolic Flexibility of Neurotransmission.

Ashrafi G, de Juan-Sanz J, Farrell RJ, Ryan TA. Ashrafi G, et al. Neuron. 2020 Feb 19;105(4):678-687.e5. doi: 10.1016/j.neuron.2019.11.020. Epub 2019 Dec 17. Neuron. 2020. PMID: 31862210 Free PMC article.

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