Chen KF - Search Results

1

RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells.

Su JC, Chiang HC, Tseng PH, Tai WT, Hsu CY, Li YS, Huang JW, Ko CH, Lin MW, Chu PY, Liu CY, Chen KF, Shiau CW. Su JC, et al. Among authors: chen kf. Carcinogenesis. 2014 Dec;35(12):2807-14. doi: 10.1093/carcin/bgu210. Epub 2014 Oct 16. Carcinogenesis. 2014. PMID: 25322871

2

Sorafenib overcomes TRAIL resistance of hepatocellular carcinoma cells through the inhibition of STAT3.

Chen KF, Tai WT, Liu TH, Huang HP, Lin YC, Shiau CW, Li PK, Chen PJ, Cheng AL. Chen KF, et al. Among authors: chen pj. Clin Cancer Res. 2010 Nov 1;16(21):5189-99. doi: 10.1158/1078-0432.CCR-09-3389. Epub 2010 Sep 30. Clin Cancer Res. 2010. PMID: 20884624

3

Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells.

Chen KF, Chen HL, Tai WT, Feng WC, Hsu CH, Chen PJ, Cheng AL. Chen KF, et al. Among authors: chen hl, chen pj. J Pharmacol Exp Ther. 2011 Apr;337(1):155-61. doi: 10.1124/jpet.110.175786. Epub 2011 Jan 4. J Pharmacol Exp Ther. 2011. PMID: 21205925

4

Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma.

Tai WT, Cheng AL, Shiau CW, Huang HP, Huang JW, Chen PJ, Chen KF. Tai WT, et al. Among authors: chen pj, chen kf. J Hepatol. 2011 Nov;55(5):1041-8. doi: 10.1016/j.jhep.2011.01.047. Epub 2011 Feb 24. J Hepatol. 2011. PMID: 21354226

5

Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3.

Tai WT, Cheng AL, Shiau CW, Liu CY, Ko CH, Lin MW, Chen PJ, Chen KF. Tai WT, et al. Among authors: chen pj, chen kf. Mol Cancer Ther. 2012 Feb;11(2):452-63. doi: 10.1158/1535-7163.MCT-11-0412. Epub 2011 Dec 16. Mol Cancer Ther. 2012. PMID: 22180308

6

Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3.

Chen KF, Chen HL, Liu CY, Tai WT, Ichikawa K, Chen PJ, Cheng AL. Chen KF, et al. Among authors: chen hl, chen pj. Biochem Pharmacol. 2012 Mar 15;83(6):769-77. doi: 10.1016/j.bcp.2011.12.035. Epub 2012 Jan 2. Biochem Pharmacol. 2012. PMID: 22230479

7

A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation.

Chen KF, Su JC, Liu CY, Huang JW, Chen KC, Chen WL, Tai WT, Shiau CW. Chen KF, et al. Among authors: chen wl, chen kc. Cancer Lett. 2012 Aug 1;321(1):27-35. doi: 10.1016/j.canlet.2012.03.023. Epub 2012 Mar 28. Cancer Lett. 2012. PMID: 22465052

8

Inhibition of Bcl-2 improves effect of LCL161, a SMAC mimetic, in hepatocellular carcinoma cells.

Chen KF, Lin JP, Shiau CW, Tai WT, Liu CY, Yu HC, Chen PJ, Cheng AL. Chen KF, et al. Among authors: chen pj. Biochem Pharmacol. 2012 Aug 1;84(3):268-77. doi: 10.1016/j.bcp.2012.04.023. Epub 2012 May 9. Biochem Pharmacol. 2012. PMID: 22580047

9

Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity.

Chen KF, Tai WT, Hsu CY, Huang JW, Liu CY, Chen PJ, Kim I, Shiau CW. Chen KF, et al. Among authors: chen pj. Eur J Med Chem. 2012 Sep;55:220-7. doi: 10.1016/j.ejmech.2012.07.023. Epub 2012 Jul 23. Eur J Med Chem. 2012. PMID: 22871485

10

SC-1, a sorafenib derivative, shows anti-tumor effects in osteogenic sarcoma cells.

Wang CT, Lin CS, Shiau CW, Chu PY, Hsiao CC, Chiang YL, Tai WT, Chen KF. Wang CT, et al. Among authors: chen kf. J Orthop Res. 2013 Feb;31(2):335-42. doi: 10.1002/jor.22218. Epub 2012 Aug 23. J Orthop Res. 2013. PMID: 22926753 Free article.

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