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Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors.
Lukens AK, Heidebrecht RW Jr, Mulrooney C, Beaudoin JA, Comer E, Duvall JR, Fitzgerald ME, Masi D, Galinsky K, Scherer CA, Palmer M, Munoz B, Foley M, Schreiber SL, Wiegand RC, Wirth DF. Lukens AK, et al. Among authors: schreiber sl. J Infect Dis. 2015 Apr 1;211(7):1097-103. doi: 10.1093/infdis/jiu565. Epub 2014 Oct 21. J Infect Dis. 2015. PMID: 25336726 Free PMC article.
A one-bead, one-stock solution approach to chemical genetics: part 1.
Blackwell HE, Pérez L, Stavenger RA, Tallarico JA, Cope Eatough E, Foley MA, Schreiber SL. Blackwell HE, et al. Among authors: schreiber sl. Chem Biol. 2001 Dec;8(12):1167-82. doi: 10.1016/s1074-5521(01)00085-0. Chem Biol. 2001. PMID: 11755396
A one-bead, one-stock solution approach to chemical genetics: part 2.
Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. Clemons PA, et al. Among authors: schreiber sl. Chem Biol. 2001 Dec;8(12):1183-95. doi: 10.1016/s1074-5521(01)00086-2. Chem Biol. 2001. PMID: 11755397
Towards patient-based cancer therapeutics.
Cancer Target Discovery and Development Network; Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, Sordella R, Stein L, Trotman LC, Califano A, Dalla-Favera R, Ferrando A, Iavarone A, Pasqualucci L, Silva J, Stockwell BR, Hahn WC, Chin L, DePinho RA, Boehm JS, Gopal S, Huang A, Root DE, Weir BA, Gerhard DS, Zenklusen JC, Roth MG, White MA, Minna JD, MacMillan JB, Posner BA. Cancer Target Discovery and Development Network, et al. Among authors: schreiber sl. Nat Biotechnol. 2010 Sep;28(9):904-6. doi: 10.1038/nbt0910-904. Nat Biotechnol. 2010. PMID: 20829823 Free PMC article.
AAK1 identified as an inhibitor of neuregulin-1/ErbB4-dependent neurotrophic factor signaling using integrative chemical genomics and proteomics.
Kuai L, Ong SE, Madison JM, Wang X, Duvall JR, Lewis TA, Luce CJ, Conner SD, Pearlman DA, Wood JL, Schreiber SL, Carr SA, Scolnick EM, Haggarty SJ. Kuai L, et al. Among authors: schreiber sl. Chem Biol. 2011 Jul 29;18(7):891-906. doi: 10.1016/j.chembiol.2011.03.017. Chem Biol. 2011. PMID: 21802010 Free PMC article.
558 results