Shapiro IM - Search Results

1

Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.

Merceron C, Mangiavini L, Robling A, Wilson TL, Giaccia AJ, Shapiro IM, Schipani E, Risbud MV. Merceron C, et al. Among authors: shapiro im. PLoS One. 2014 Oct 22;9(10):e110768. doi: 10.1371/journal.pone.0110768. eCollection 2014. PLoS One. 2014. PMID: 25338007 Free PMC article.

2

Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment.

Risbud MV, Guttapalli A, Stokes DG, Hawkins D, Danielson KG, Schaer TP, Albert TJ, Shapiro IM. Risbud MV, et al. Among authors: shapiro im. J Cell Biochem. 2006 May 1;98(1):152-9. doi: 10.1002/jcb.20765. J Cell Biochem. 2006. PMID: 16408279

3

Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk.

Agrawal A, Guttapalli A, Narayan S, Albert TJ, Shapiro IM, Risbud MV. Agrawal A, et al. Among authors: shapiro im. Am J Physiol Cell Physiol. 2007 Aug;293(2):C621-31. doi: 10.1152/ajpcell.00538.2006. Epub 2007 Apr 18. Am J Physiol Cell Physiol. 2007. PMID: 17442734 Free article.

4

HIF-1 alpha is a regulator of galectin-3 expression in the intervertebral disc.

Zeng Y, Danielson KG, Albert TJ, Shapiro IM, Risbud MV. Zeng Y, et al. Among authors: shapiro im. J Bone Miner Res. 2007 Dec;22(12):1851-61. doi: 10.1359/jbmr.070620. J Bone Miner Res. 2007. PMID: 17592963 Free article.

5

Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc.

Agrawal A, Gajghate S, Smith H, Anderson DG, Albert TJ, Shapiro IM, Risbud MV. Agrawal A, et al. Among authors: shapiro im. Arthritis Rheum. 2008 Dec;58(12):3798-808. doi: 10.1002/art.24073. Arthritis Rheum. 2008. PMID: 19035510 Free article.

6

Hypoxic regulation of nucleus pulposus cell survival: from niche to notch.

Risbud MV, Schipani E, Shapiro IM. Risbud MV, et al. Among authors: shapiro im. Am J Pathol. 2010 Apr;176(4):1577-83. doi: 10.2353/ajpath.2010.090734. Epub 2010 Feb 4. Am J Pathol. 2010. PMID: 20133815 Free PMC article. Review.

7

Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord.

Risbud MV, Schaer TP, Shapiro IM. Risbud MV, et al. Among authors: shapiro im. Dev Dyn. 2010 Aug;239(8):2141-8. doi: 10.1002/dvdy.22350. Dev Dyn. 2010. PMID: 20568241 Free PMC article. Review.

8

Hypoxic regulation of β-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: role of hypoxia-inducible factor proteins.

Gogate SS, Nasser R, Shapiro IM, Risbud MV. Gogate SS, et al. Among authors: shapiro im. Arthritis Rheum. 2011 Jul;63(7):1950-60. doi: 10.1002/art.30342. Arthritis Rheum. 2011. PMID: 21400481 Free PMC article.

9

Notochordal cells in the adult intervertebral disc: new perspective on an old question.

Risbud MV, Shapiro IM. Risbud MV, et al. Among authors: shapiro im. Crit Rev Eukaryot Gene Expr. 2011;21(1):29-41. doi: 10.1615/critreveukargeneexpr.v21.i1.30. Crit Rev Eukaryot Gene Expr. 2011. PMID: 21967331 Free PMC article. Review.

10

HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc.

Fujita N, Chiba K, Shapiro IM, Risbud MV. Fujita N, et al. Among authors: shapiro im. J Bone Miner Res. 2012 Feb;27(2):401-12. doi: 10.1002/jbmr.538. J Bone Miner Res. 2012. PMID: 21987385 Free PMC article.

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