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Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides.
Thakare R, Gao H, Kosa RE, Bi YA, Varma MVS, Cerny MA, Sharma R, Kuhn M, Huang B, Liu Y, Yu A, Walker GS, Niosi M, Tremaine L, Alnouti Y, Rodrigues AD. Thakare R, et al. Drug Metab Dispos. 2017 Jul;45(7):721-733. doi: 10.1124/dmd.117.075275. Epub 2017 Apr 10. Drug Metab Dispos. 2017. PMID: 28396527
Peripherally cross-linking the shell of core-shell polymer micelles decreases premature release of physically loaded combretastatin A4 in whole blood and increases its mean residence time and subsequent potency against primary murine breast tumors after IV administration.
Wakaskar RR, Bathena SP, Tallapaka SB, Ambardekar VV, Gautam N, Thakare R, Simet SM, Curran SM, Singh RK, Dong Y, Vetro JA. Wakaskar RR, et al. Among authors: thakare r. Pharm Res. 2015 Mar;32(3):1028-44. doi: 10.1007/s11095-014-1515-z. Epub 2014 Sep 16. Pharm Res. 2015. PMID: 25223962 Free PMC article.
Quantitative analysis of endogenous compounds.
Thakare R, Chhonker YS, Gautam N, Alamoudi JA, Alnouti Y. Thakare R, et al. J Pharm Biomed Anal. 2016 Sep 5;128:426-437. doi: 10.1016/j.jpba.2016.06.017. Epub 2016 Jun 11. J Pharm Biomed Anal. 2016. PMID: 27344632 Review.
51 results