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Page 1
Cyclin C is a haploinsufficient tumour suppressor.
Li N, Fassl A, Chick J, Inuzuka H, Li X, Mansour MR, Liu L, Wang H, King B, Shaik S, Gutierrez A, Ordureau A, Otto T, Kreslavsky T, Baitsch L, Bury L, Meyer CA, Ke N, Mulry KA, Kluk MJ, Roy M, Kim S, Zhang X, Geng Y, Zagozdzon A, Jenkinson S, Gale RE, Linch DC, Zhao JJ, Mullighan CG, Harper JW, Aster JC, Aifantis I, von Boehmer H, Gygi SP, Wei W, Look AT, Sicinski P. Li N, et al. Among authors: geng y. Nat Cell Biol. 2014 Nov;16(11):1080-91. doi: 10.1038/ncb3046. Epub 2014 Oct 26. Nat Cell Biol. 2014. PMID: 25344755 Free PMC article.
G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells.
Liu L, Michowski W, Inuzuka H, Shimizu K, Nihira NT, Chick JM, Li N, Geng Y, Meng AY, Ordureau A, Kołodziejczyk A, Ligon KL, Bronson RT, Polyak K, Harper JW, Gygi SP, Wei W, Sicinski P. Liu L, et al. Among authors: geng y. Nat Cell Biol. 2017 Mar;19(3):177-188. doi: 10.1038/ncb3474. Epub 2017 Feb 13. Nat Cell Biol. 2017. PMID: 28192421 Free PMC article.
The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival.
Wang H, Nicolay BN, Chick JM, Gao X, Geng Y, Ren H, Gao H, Yang G, Williams JA, Suski JM, Keibler MA, Sicinska E, Gerdemann U, Haining WN, Roberts TM, Polyak K, Gygi SP, Dyson NJ, Sicinski P. Wang H, et al. Among authors: geng y. Nature. 2017 Jun 15;546(7658):426-430. doi: 10.1038/nature22797. Epub 2017 Jun 7. Nature. 2017. PMID: 28607489 Free PMC article.
Cyclin E in normal physiology and disease states.
Chu C, Geng Y, Zhou Y, Sicinski P. Chu C, et al. Among authors: geng y. Trends Cell Biol. 2021 Sep;31(9):732-746. doi: 10.1016/j.tcb.2021.05.001. Epub 2021 May 27. Trends Cell Biol. 2021. PMID: 34052101 Free PMC article. Review.
Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.
Bienvenu F, Jirawatnotai S, Elias JE, Meyer CA, Mizeracka K, Marson A, Frampton GM, Cole MF, Odom DT, Odajima J, Geng Y, Zagozdzon A, Jecrois M, Young RA, Liu XS, Cepko CL, Gygi SP, Sicinski P. Bienvenu F, et al. Among authors: geng y. Nature. 2010 Jan 21;463(7279):374-8. doi: 10.1038/nature08684. Nature. 2010. PMID: 20090754 Free PMC article.
Kinase-independent function of E-type cyclins in liver cancer.
Geng Y, Michowski W, Chick JM, Wang YE, Jecrois ME, Sweeney KE, Liu L, Han RC, Ke N, Zagozdzon A, Sicinska E, Bronson RT, Gygi SP, Sicinski P. Geng Y, et al. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):1015-1020. doi: 10.1073/pnas.1711477115. Epub 2018 Jan 16. Proc Natl Acad Sci U S A. 2018. PMID: 29339491 Free PMC article.
Targeting the cyclin-dependent kinase 5 in metastatic melanoma.
Sharma S, Zhang T, Michowski W, Rebecca VW, Xiao M, Ferretti R, Suski JM, Bronson RT, Paulo JA, Frederick D, Fassl A, Boland GM, Geng Y, Lees JA, Medema RH, Herlyn M, Gygi SP, Sicinski P. Sharma S, et al. Among authors: geng y. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8001-8012. doi: 10.1073/pnas.1912617117. Epub 2020 Mar 19. Proc Natl Acad Sci U S A. 2020. PMID: 32193336 Free PMC article.
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy.
Gao Y, Nihira NT, Bu X, Chu C, Zhang J, Kolodziejczyk A, Fan Y, Chan NT, Ma L, Liu J, Wang D, Dai X, Liu H, Ono M, Nakanishi A, Inuzuka H, North BJ, Huang YH, Sharma S, Geng Y, Xu W, Liu XS, Li L, Miki Y, Sicinski P, Freeman GJ, Wei W. Gao Y, et al. Among authors: geng y. Nat Cell Biol. 2020 Sep;22(9):1064-1075. doi: 10.1038/s41556-020-0562-4. Epub 2020 Aug 24. Nat Cell Biol. 2020. PMID: 32839551 Free PMC article.
The requirement for cyclin E in c-Myc overexpressing breast cancers.
Zhou Y, Geng Y, Zhang Y, Zhou Y, Chu C, Sharma S, Fassl A, Butter D, Sicinski P. Zhou Y, et al. Among authors: geng y. Cell Cycle. 2020 Oct;19(20):2589-2599. doi: 10.1080/15384101.2020.1804720. Epub 2020 Sep 25. Cell Cycle. 2020. PMID: 32975478 Free PMC article.
4,015 results