AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif.
Kyttälä A, Yliannala K, Schu P, Jalanko A, Luzio JP.
Kyttälä A, et al.
J Biol Chem. 2005 Mar 18;280(11):10277-83. doi: 10.1074/jbc.M411862200. Epub 2004 Dec 13.
J Biol Chem. 2005.
PMID: 15598649
Free article.
CLN3 is a transmembrane protein with a predominant localization in lysosomes in non-neuronal cells but is also found in endosomes and the synaptic region in neuronal cells. ...We have recently reported that the lysosomal targeting of CLN3 is facilitated by two targe …
CLN3 is a transmembrane protein with a predominant localization in lysosomes in non-neuronal cells but is also found in endoso …