Chandrashekaran IR - Search Results

1

Structure and dynamics of apical membrane antigen 1 from Plasmodium falciparum FVO.

Lim SS, Yang W, Krishnarjuna B, Kannan Sivaraman K, Chandrashekaran IR, Kass I, MacRaild CA, Devine SM, Debono CO, Anders RF, Scanlon MJ, Scammells PJ, Norton RS, McGowan S. Lim SS, et al. Among authors: chandrashekaran ir. Biochemistry. 2014 Nov 25;53(46):7310-20. doi: 10.1021/bi5012089. Epub 2014 Nov 14. Biochemistry. 2014. PMID: 25360546

2

The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs.

Chandrashekaran IR, Yao S, Wang CC, Bansal PS, Alewood PF, Forbes BE, Wallace JC, Bach LA, Norton RS. Chandrashekaran IR, et al. Biochemistry. 2007 Mar 20;46(11):3065-74. doi: 10.1021/bi0619876. Epub 2007 Feb 17. Biochemistry. 2007. PMID: 17305365

3

Merozoite surface protein 2 of Plasmodium falciparum: expression, structure, dynamics, and fibril formation of the conserved N-terminal domain.

Low A, Chandrashekaran IR, Adda CG, Yao S, Sabo JK, Zhang X, Soetopo A, Anders RF, Norton RS. Low A, et al. Among authors: chandrashekaran ir. Biopolymers. 2007 Sep;87(1):12-22. doi: 10.1002/bip.20764. Biopolymers. 2007. PMID: 17516503

4

Inhibition by flavonoids of amyloid-like fibril formation by Plasmodium falciparum merozoite surface protein 2.

Chandrashekaran IR, Adda CG, MacRaild CA, Anders RF, Norton RS. Chandrashekaran IR, et al. Biochemistry. 2010 Jul 20;49(28):5899-908. doi: 10.1021/bi902197x. Biochemistry. 2010. PMID: 20545323

5

EGCG disaggregates amyloid-like fibrils formed by Plasmodium falciparum merozoite surface protein 2.

Chandrashekaran IR, Adda CG, Macraild CA, Anders RF, Norton RS. Chandrashekaran IR, et al. Arch Biochem Biophys. 2011 Sep 15;513(2):153-7. doi: 10.1016/j.abb.2011.07.008. Epub 2011 Jul 19. Arch Biochem Biophys. 2011. PMID: 21784057 Free PMC article.

6

The N-terminal domains of SOCS proteins: a conserved region in the disordered N-termini of SOCS4 and 5.

Feng ZP, Chandrashekaran IR, Low A, Speed TP, Nicholson SE, Norton RS. Feng ZP, et al. Among authors: chandrashekaran ir. Proteins. 2012 Mar;80(3):946-57. doi: 10.1002/prot.23252. Proteins. 2012. PMID: 22423360

7

Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.

Linossi EM, Chandrashekaran IR, Kolesnik TB, Murphy JM, Webb AI, Willson TA, Kedzierski L, Bullock AN, Babon JJ, Norton RS, Nicola NA, Nicholson SE. Linossi EM, et al. Among authors: chandrashekaran ir. PLoS One. 2013 Aug 21;8(8):e70536. doi: 10.1371/journal.pone.0070536. eCollection 2013. PLoS One. 2013. PMID: 23990909 Free PMC article.

8

Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold.

Devine SM, Mulcair MD, Debono CO, Leung EW, Nissink JW, Lim SS, Chandrashekaran IR, Vazirani M, Mohanty B, Simpson JS, Baell JB, Scammells PJ, Norton RS, Scanlon MJ. Devine SM, et al. Among authors: chandrashekaran ir. J Med Chem. 2015 Feb 12;58(3):1205-14. doi: 10.1021/jm501402x. Epub 2015 Jan 16. J Med Chem. 2015. PMID: 25559643

9

Structure and Functional Characterization of the Conserved JAK Interaction Region in the Intrinsically Disordered N-Terminus of SOCS5.

Chandrashekaran IR, Mohanty B, Linossi EM, Dagley LF, Leung EW, Murphy JM, Babon JJ, Nicholson SE, Norton RS. Chandrashekaran IR, et al. Biochemistry. 2015 Aug 4;54(30):4672-82. doi: 10.1021/acs.biochem.5b00619. Epub 2015 Jul 27. Biochemistry. 2015. PMID: 26173083

10

Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials.

Krishnarjuna B, Lim SS, Devine SM, Debono CO, Lam R, Chandrashekaran IR, Jaipuria G, Yagi H, Atreya HS, Scanlon MJ, MacRaild CA, Scammells PJ, Norton RS. Krishnarjuna B, et al. Among authors: chandrashekaran ir. J Mol Recognit. 2016 Jun;29(6):281-91. doi: 10.1002/jmr.2529. Epub 2016 Jan 24. J Mol Recognit. 2016. PMID: 26804042

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