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Isoliquiritigenin induces apoptosis and inhibits xenograft tumor growth of human lung cancer cells by targeting both wild type and L858R/T790M mutant EGFR.
Jung SK, Lee MH, Lim DY, Kim JE, Singh P, Lee SY, Jeong CH, Lim TG, Chen H, Chi YI, Kundu JK, Lee NH, Lee CC, Cho YY, Bode AM, Lee KW, Dong Z. Jung SK, et al. Among authors: chi yi. J Biol Chem. 2014 Dec 26;289(52):35839-48. doi: 10.1074/jbc.M114.585513. Epub 2014 Nov 3. J Biol Chem. 2014. PMID: 25368326 Free PMC article.
Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia.
Dou L, Yan F, Pang J, Zheng D, Li D, Gao L, Wang L, Xu Y, Shi J, Wang Q, Zhou L, Shen N, Singh P, Wang L, Li Y, Gao Y, Liu T, Chen C, Al-Kali A, Litzow MR, Chi YI, Bode AM, Liu C, Huang H, Liu D, Marcucci G, Liu S, Yu L. Dou L, et al. Among authors: chi yi. Nat Commun. 2019 Nov 7;10(1):5051. doi: 10.1038/s41467-019-12960-6. Nat Commun. 2019. PMID: 31699991 Free PMC article.
Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases.
Lee D, Pagire HS, Pagire SH, Bae EJ, Dighe M, Kim M, Lee KM, Jang YK, Jaladi AK, Jung KY, Yoo EK, Gim HE, Lee S, Choi WI, Chi YI, Song JS, Bae MA, Jeon YH, Lee GH, Liu KH, Lee T, Park S, Jeon JH, Lee IK, Ahn JH. Lee D, et al. Among authors: chi yi. J Med Chem. 2019 Jan 24;62(2):575-588. doi: 10.1021/acs.jmedchem.8b01168. Epub 2019 Jan 9. J Med Chem. 2019. PMID: 30623649
114 results