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Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.
Elliott JH, Wightman F, Solomon A, Ghneim K, Ahlers J, Cameron MJ, Smith MZ, Spelman T, McMahon J, Velayudham P, Brown G, Roney J, Watson J, Prince MH, Hoy JF, Chomont N, Fromentin R, Procopio FA, Zeidan J, Palmer S, Odevall L, Johnstone RW, Martin BP, Sinclair E, Deeks SG, Hazuda DJ, Cameron PU, Sékaly RP, Lewin SR. Elliott JH, et al. Among authors: sekaly rp. PLoS Pathog. 2014 Nov 13;10(10):e1004473. doi: 10.1371/journal.ppat.1004473. eCollection 2014 Oct. PLoS Pathog. 2014. PMID: 25393648 Free PMC article. Clinical Trial.
Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.
van Grevenynghe J, Procopio FA, He Z, Chomont N, Riou C, Zhang Y, Gimmig S, Boucher G, Wilkinson P, Shi Y, Yassine-Diab B, Said EA, Trautmann L, El Far M, Balderas RS, Boulassel MR, Routy JP, Haddad EK, Sekaly RP. van Grevenynghe J, et al. Among authors: sekaly rp. Nat Med. 2008 Mar;14(3):266-74. doi: 10.1038/nm1728. Epub 2008 Mar 2. Nat Med. 2008. PMID: 18311149
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.
Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, Boucher G, Boulassel MR, Ghattas G, Brenchley JM, Schacker TW, Hill BJ, Douek DC, Routy JP, Haddad EK, Sékaly RP. Chomont N, et al. Among authors: sekaly rp. Nat Med. 2009 Aug;15(8):893-900. doi: 10.1038/nm.1972. Epub 2009 Jun 21. Nat Med. 2009. PMID: 19543283 Free PMC article. Clinical Trial.
Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton.
Cameron PU, Saleh S, Sallmann G, Solomon A, Wightman F, Evans VA, Boucher G, Haddad EK, Sekaly RP, Harman AN, Anderson JL, Jones KL, Mak J, Cunningham AL, Jaworowski A, Lewin SR. Cameron PU, et al. Among authors: sekaly rp. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16934-9. doi: 10.1073/pnas.1002894107. Epub 2010 Sep 13. Proc Natl Acad Sci U S A. 2010. PMID: 20837531 Free PMC article.
393 results