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Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model.
Yan J, Tingey C, Lyde R, Gorham TC, Choo DK, Muthumani A, Myles D, Weiner LP, Kraynyak KA, Reuschel EL, Finkel TH, Kim JJ, Sardesai NY, Ugen KE, Muthumani K, Weiner DB. Yan J, et al. Among authors: reuschel el. Cancer Gene Ther. 2014 Dec;21(12):507-17. doi: 10.1038/cgt.2014.56. Epub 2014 Nov 14. Cancer Gene Ther. 2014. PMID: 25394503
REDD1 Is Essential for Optimal T Cell Proliferation and Survival.
Reuschel EL, Wang J, Shivers DK, Muthumani K, Weiner DB, Ma Z, Finkel TH. Reuschel EL, et al. PLoS One. 2015 Aug 24;10(8):e0136323. doi: 10.1371/journal.pone.0136323. eCollection 2015. PLoS One. 2015. PMID: 26301899 Free PMC article.
Rapid and Long-Term Immunity Elicited by DNA-Encoded Antibody Prophylaxis and DNA Vaccination Against Chikungunya Virus.
Muthumani K, Block P, Flingai S, Muruganantham N, Chaaithanya IK, Tingey C, Wise M, Reuschel EL, Chung C, Muthumani A, Sarangan G, Srikanth P, Khan AS, Vijayachari P, Sardesai NY, Kim JJ, Ugen KE, Weiner DB. Muthumani K, et al. Among authors: reuschel el. J Infect Dis. 2016 Aug 1;214(3):369-78. doi: 10.1093/infdis/jiw111. Epub 2016 Mar 21. J Infect Dis. 2016. PMID: 27001960 Free PMC article.
Novel prostate cancer immunotherapy with a DNA-encoded anti-prostate-specific membrane antigen monoclonal antibody.
Muthumani K, Marnin L, Kudchodkar SB, Perales-Puchalt A, Choi H, Agarwal S, Scott VL, Reuschel EL, Zaidi FI, Duperret EK, Wise MC, Kraynyak KA, Ugen KE, Sardesai NY, Joseph Kim J, Weiner DB. Muthumani K, et al. Among authors: reuschel el. Cancer Immunol Immunother. 2017 Dec;66(12):1577-1588. doi: 10.1007/s00262-017-2042-7. Epub 2017 Aug 17. Cancer Immunol Immunother. 2017. PMID: 28819703 Free PMC article.
A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus.
Choi H, Kudchodkar SB, Ho M, Reuschel EL, Reynolds E, Xu Z, Bordoloi D, Ugen KE, Tebas P, Kim J, Abdel-Mohsen M, Thangamani S, Weiner DB, Muthumani K. Choi H, et al. Among authors: reuschel el. PLoS Negl Trop Dis. 2020 Oct 29;14(10):e0008788. doi: 10.1371/journal.pntd.0008788. eCollection 2020 Oct. PLoS Negl Trop Dis. 2020. PMID: 33119599 Free PMC article.
A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates.
Muthumani K, Falzarano D, Reuschel EL, Tingey C, Flingai S, Villarreal DO, Wise M, Patel A, Izmirly A, Aljuaid A, Seliga AM, Soule G, Morrow M, Kraynyak KA, Khan AS, Scott DP, Feldmann F, LaCasse R, Meade-White K, Okumura A, Ugen KE, Sardesai NY, Kim JJ, Kobinger G, Feldmann H, Weiner DB. Muthumani K, et al. Among authors: reuschel el. Sci Transl Med. 2015 Aug 19;7(301):301ra132. doi: 10.1126/scitranslmed.aac7462. Sci Transl Med. 2015. PMID: 26290414 Free PMC article.
Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity.
Shedlock DJ, Tingey C, Mahadevan L, Hutnick N, Reuschel EL, Kudchodkar S, Flingai S, Yan J, Kim JJ, Ugen KE, Weiner DB, Muthumani K. Shedlock DJ, et al. Among authors: reuschel el. Vaccines (Basel). 2014 Mar 25;2(2):196-215. doi: 10.3390/vaccines2020196. Vaccines (Basel). 2014. PMID: 26344618 Free PMC article.
Synthetic nucleic acid antibody prophylaxis confers rapid and durable protective immunity against Zika virus challenge.
Choi H, Kudchodkar SB, Reuschel EL, Asija K, Borole P, Agarwal S, Van Gorder L, Reed CC, Gulendran G, Ramos S, Broderick KE, Kim JJ, Ugen KE, Kobinger G, Siegel DL, Weiner DB, Muthumani K. Choi H, et al. Among authors: reuschel el. Hum Vaccin Immunother. 2020 Apr 2;16(4):907-918. doi: 10.1080/21645515.2019.1688038. Epub 2019 Dec 4. Hum Vaccin Immunother. 2020. PMID: 31799896 Free PMC article.
In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine.
Muthumani K, Griffin BD, Agarwal S, Kudchodkar SB, Reuschel EL, Choi H, Kraynyak KA, Duperret EK, Keaton AA, Chung C, Kim YK, Booth SA, Racine T, Yan J, Morrow MP, Jiang J, Lee B, Ramos S, Broderick KE, Reed CC, Khan AS, Humeau L, Ugen KE, Park YK, Maslow JN, Sardesai NY, Joseph Kim J, Kobinger GP, Weiner DB. Muthumani K, et al. Among authors: reuschel el. NPJ Vaccines. 2016 Nov 10;1:16021. doi: 10.1038/npjvaccines.2016.21. eCollection 2016. NPJ Vaccines. 2016. PMID: 29263859 Free PMC article.
30 results