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Page 1
Genomics illuminates parasite biology.
Foth BJ, Otto TD. Foth BJ, et al. Among authors: otto td. Nat Rev Microbiol. 2014 Nov;12(11):727. doi: 10.1038/nrmicro3368. Nat Rev Microbiol. 2014. PMID: 25402362 No abstract available.
Efficient depletion of host DNA contamination in malaria clinical sequencing.
Oyola SO, Gu Y, Manske M, Otto TD, O'Brien J, Alcock D, Macinnis B, Berriman M, Newbold CI, Kwiatkowski DP, Swerdlow HP, Quail MA. Oyola SO, et al. Among authors: otto td. J Clin Microbiol. 2013 Mar;51(3):745-51. doi: 10.1128/JCM.02507-12. Epub 2012 Dec 5. J Clin Microbiol. 2013. PMID: 23224084 Free PMC article.
Cereal killers.
Otto TD, Reid AJ. Otto TD, et al. Nat Rev Microbiol. 2013 Nov;11(11):744. doi: 10.1038/nrmicro3144. Nat Rev Microbiol. 2013. PMID: 24129509 No abstract available.
A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.
Sinha A, Hughes KR, Modrzynska KK, Otto TD, Pfander C, Dickens NJ, Religa AA, Bushell E, Graham AL, Cameron R, Kafsack BFC, Williams AE, Llinas M, Berriman M, Billker O, Waters AP. Sinha A, et al. Among authors: otto td. Nature. 2014 Mar 13;507(7491):253-257. doi: 10.1038/nature12970. Epub 2014 Feb 23. Nature. 2014. PMID: 24572359 Free PMC article.
Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum.
Vaidya AB, Morrisey JM, Zhang Z, Das S, Daly TM, Otto TD, Spillman NJ, Wyvratt M, Siegl P, Marfurt J, Wirjanata G, Sebayang BF, Price RN, Chatterjee A, Nagle A, Stasiak M, Charman SA, Angulo-Barturen I, Ferrer S, Belén Jiménez-Díaz M, Martínez MS, Gamo FJ, Avery VM, Ruecker A, Delves M, Kirk K, Berriman M, Kortagere S, Burrows J, Fan E, Bergman LW. Vaidya AB, et al. Among authors: otto td. Nat Commun. 2014 Nov 25;5:5521. doi: 10.1038/ncomms6521. Nat Commun. 2014. PMID: 25422853 Free PMC article.
A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Baragaña B, Hallyburton I, Lee MC, Norcross NR, Grimaldi R, Otto TD, Proto WR, Blagborough AM, Meister S, Wirjanata G, Ruecker A, Upton LM, Abraham TS, Almeida MJ, Pradhan A, Porzelle A, Luksch T, Martínez MS, Luksch T, Bolscher JM, Woodland A, Norval S, Zuccotto F, Thomas J, Simeons F, Stojanovski L, Osuna-Cabello M, Brock PM, Churcher TS, Sala KA, Zakutansky SE, Jiménez-Díaz MB, Sanz LM, Riley J, Basak R, Campbell M, Avery VM, Sauerwein RW, Dechering KJ, Noviyanti R, Campo B, Frearson JA, Angulo-Barturen I, Ferrer-Bazaga S, Gamo FJ, Wyatt PG, Leroy D, Siegl P, Delves MJ, Kyle DE, Wittlin S, Marfurt J, Price RN, Sinden RE, Winzeler EA, Charman SA, Bebrevska L, Gray DW, Campbell S, Fairlamb AH, Willis PA, Rayner JC, Fidock DA, Read KD, Gilbert IH. Baragaña B, et al. Among authors: otto td. Nature. 2015 Jun 18;522(7556):315-20. doi: 10.1038/nature14451. Nature. 2015. PMID: 26085270 Free PMC article.
Companion: a web server for annotation and analysis of parasite genomes.
Steinbiss S, Silva-Franco F, Brunk B, Foth B, Hertz-Fowler C, Berriman M, Otto TD. Steinbiss S, et al. Among authors: otto td. Nucleic Acids Res. 2016 Jul 8;44(W1):W29-34. doi: 10.1093/nar/gkw292. Epub 2016 Apr 21. Nucleic Acids Res. 2016. PMID: 27105845 Free PMC article.
Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host.
Klemm EJ, Gkrania-Klotsas E, Hadfield J, Forbester JL, Harris SR, Hale C, Heath JN, Wileman T, Clare S, Kane L, Goulding D, Otto TD, Kay S, Doffinger R, Cooke FJ, Carmichael A, Lever AM, Parkhill J, MacLennan CA, Kumararatne D, Dougan G, Kingsley RA. Klemm EJ, et al. Among authors: otto td. Nat Microbiol. 2016 Mar;1(3):15023. doi: 10.1038/nmicrobiol.2015.23. Epub 2016 Jan 25. Nat Microbiol. 2016. PMID: 27127642 Free PMC article.
154 results